Neutrophil function: from mechanisms to disease

B Amulic, C Cazalet, GL Hayes… - Annual review of …, 2012 - annualreviews.org
Neutrophils are the most abundant white blood cells in circulation, and patients with
congenital neutrophil deficiencies suffer from severe infections that are often fatal …

The jam session between muscle stem cells and the extracellular matrix in the tissue microenvironment

M Loreti, A Sacco - NPJ Regenerative medicine, 2022 - nature.com
Skeletal muscle requires a highly orchestrated coordination between multiple cell types and
their microenvironment to exert its function and to maintain its homeostasis and regenerative …

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

C Schauer, C Janko, LE Munoz, Y Zhao, D Kienhöfer… - Nature medicine, 2014 - nature.com
Gout is characterized by an acute inflammatory reaction and the accumulation of neutrophils
in response to monosodium urate (MSU) crystals. Inflammation resolves spontaneously …

Neutrophils cascading their way to inflammation

CD Sadik, ND Kim, AD Luster - Trends in immunology, 2011 - cell.com
Neutrophils are pivotal effector cells of innate immunity. Their recruitment into peripheral
tissues is indispensable for host defense. Given their destructive potential, neutrophil entry …

A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs

MF Denny, S Yalavarthi, W Zhao… - The journal of …, 2010 - journals.aai.org
Neutrophil-specific genes are abundant in PBMC microarrays from lupus patients because
of the presence of low-density granulocytes (LDGs) in mononuclear cell fractions. The …

Targeting inflammation in metabolic syndrome

FK Welty, A Alfaddagh, TK Elajami - Translational research, 2016 - Elsevier
The metabolic syndrome (MetS) is comprised of a cluster of closely related risk factors,
including visceral adiposity, insulin resistance, hypertension, high triglyceride, and low high …

Key mechanisms governing resolution of lung inflammation

CT Robb, KH Regan, DA Dorward, AG Rossi - Seminars in …, 2016 - Springer
Innate immunity normally provides excellent defence against invading microorganisms.
Acute inflammation is a form of innate immune defence and represents one of the primary …

Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase …

JT Mattila, OO Ojo, D Kepka-Lenhart… - The Journal of …, 2013 - journals.aai.org
Macrophages in granulomas are both antimycobacterial effector and host cell for
Mycobacterium tuberculosis, yet basic aspects of macrophage diversity and function within …

[引用][C] Neutrophil extracellular traps (NETs)-formation and implications.

M Zawrotniak, M Rapala-Kozik - Acta Biochimica Polonica, 2013 - ojs.ptbioch.edu.pl
Neutrophils are cells of the immune system which freely circulate in blood vessels and are
recruited to the inflammation sites when the human organism responds to microbial …

NET balancing: a problem in inflammatory lung diseases

OZ Cheng, N Palaniyar - Frontiers in immunology, 2013 - frontiersin.org
Neutrophil extracellular traps (NETs) are beneficial antimicrobial defense structures that can
help fight against invading pathogens in the host. However, recent studies reveal that NETs …