Background Acute pancreatitis has long been considered a disorder of pancreatic self-
digestion, in which intracellular activation of digestive proteases induces tissue injury …

Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene
cause CF. Infants with CFTR mutations show a peribronchial neutrophil infiltration prior to …

Background: Several inflammatory hypotheses have been suggested to explain the
etiopathogenesis of bipolar disorder (BD) and its different phases. Neutrophil-to-lymphocyte …

Angiogenesis is the formation of new blood vessels from existing vessels. During RA new
blood vessels can maintain the chronic inflammatory state by transporting inflammatory cells …

The mitogen-activated protein kinase (MAPK) interacting protein kinases 1 and 2 (Mnk1 and
Mnk2) play important roles in controlling signals involved in mRNA translation. In addition to …

Iron metabolism is vital for the survival of both humans and microorganisms. Heme
oxygenase-1 (HO-1) is an essential stress-response enzyme highly expressed in the lungs …

The inflammatory process, orchestrated against a variety of injurious stimuli, is composed of
three inter-related phases; initiation, propagation and resolution. Understanding the …

Objective Chronic inflammation is associated with cardiovascular (CV) risk factors and
psychiatric disorders. The neutrophil to lymphocyte ratio (NLR) has been investigated as a …

We investigated the role of neutrophilic cells (neutrophils) in inflammatory angiogenesis and
explored the possible mechanisms involved. Corneal angiogenesis was induced in vivo with …

Physical exercise is firmly incorporated in the management of type 1 diabetes (T1DM), due
to multiple recognized beneficial health effects (cardiovascular disease prevention being …