Cysteine and homocysteine (Hcy), both sulfur‐containing amino acids (AAs), produced from
methionine another sulfur‐containing amino acid, which is converted to Hcy and further …

The pursuit to discover the fundamental biology and mechanisms of aging within the context
of the physical and social environment is critical to designing interventions to prevent and …

Elevated concentration of homocysteine (Hcy) in the blood plasma, hyperhomocysteinemia
(HHcy), has been implicated in various disorders, including cardiovascular and …

Methionine restriction (MetR) extends lifespan across different species and exerts beneficial
effects on metabolic health and inflammatory responses. In contrast, certain cancer cells …

Background During the aging process, physical capabilities (eg, muscular strength) and
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …

Increased plasma homocysteine is a risk factor for several pathological disorders. The
present review focused on the role of homocysteine (Hcy) in different population groups …

Stroke is a primary debilitating disease in adults, occurring in 15 million individuals each
year and causing high mortality and disability rates. The latest estimate revealed that stroke …

One-carbon metabolism (OCM) is a network of biochemical reactions delivering one-carbon
units to various biosynthetic pathways. The folate cycle and methionine cycle are the two key …

Objectives To evaluate the combined action of folic acid and vitamin B12 supplementation
on cognitive performance and inflammation in patients with Alzheimer's disease (AD) …

Biothiols, such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH), play a vital
role in gene expression, maintaining redox homeostasis, reducing damages caused by free …