Depression and anxiety in inflammatory bowel disease: epidemiology, mechanisms and treatment

TH Bisgaard, KH Allin, L Keefer… - Nature reviews …, 2022 - nature.com
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a
chronic, relapsing immune-mediated disease with a varying and sometimes severe disease …

Bidirectional brain–gut axis effects influence mood and prognosis in IBD: a systematic review and meta-analysis

KM Fairbrass, J Lovatt, B Barberio, Y Yuan, DJ Gracie… - Gut, 2022 - gut.bmj.com
Objective The role of the brain–gut axis is of increasing interest in IBD, as the link between
common mental disorders and GI inflammation may be bidirectional. We performed a …

Depression and anxiety in patients with active ulcerative colitis: crosstalk of gut microbiota, metabolomics and proteomics

X Yuan, B Chen, Z Duan, Z Xia, Y Ding, T Chen… - Gut …, 2021 - Taylor & Francis
Patients with ulcerative colitis (UC) have a high prevalence of mental disorders, such as
depression and anxiety. Gut microbiota imbalance and disturbed metabolism have been …

[HTML][HTML] Recognizing the role of the vagus nerve in depression from microbiota-gut brain axis

C Tan, Q Yan, Y Ma, J Fang, Y Yang - Frontiers in Neurology, 2022 - frontiersin.org
Depression is a worldwide disease causing severe disability, morbidity, and mortality.
Despite abundant studies, the precise mechanisms underlying the pathophysiology of …

[HTML][HTML] Depressive and Anxiety Disorders in Patients with Inflammatory Bowel Diseases: Are There Any Gender Differences?

E Fracas, A Costantino, M Vecchi, M Buoli - International Journal of …, 2023 - mdpi.com
Gender differences were identified in the frequency and clinical presentations of
inflammatory bowel disease (IBD) and depressive and anxiety disorders, which are more …

Microalgae‐Based Hydrogel for Inflammatory Bowel Disease and Its Associated Anxiety and Depression

D Zhong, K Jin, R Wang, B Chen, J Zhang… - Advanced …, 2024 - Wiley Online Library
Patients diagnosed with inflammatory bowel disease (IBD) exhibit a notable prevalence of
psychiatric disorders, such as anxiety and depression. Nevertheless, the etiology of …

The microbiota-gut-brain axis in pathogenesis of depression: A narrative review

H Yao, D Zhang, H Yu, H Shen, H Liu, F Meng… - Physiology & …, 2023 - Elsevier
The microbiota-gut-brain axis is a bidirectional regulatory pathway between the brain and
the gastrointestinal tract, which plays an important role in maintain homeostasis. Gut …

The association between inflammatory bowel disease and mental ill health: a retrospective cohort study using data from UK primary care

N Umar, D King, JS Chandan, N Bhala… - Alimentary …, 2022 - Wiley Online Library
Background Patients with active inflammatory bowel disease (IBD) and mental illnesses
experience worse IBD outcomes. Aim To describe the incidence of mental illnesses …

[HTML][HTML] The bidirectional risk of inflammatory bowel disease and anxiety or depression: A systematic review and meta-analysis

TH Bisgaard, KH Allin, R Elmahdi, T Jess - General Hospital Psychiatry, 2023 - Elsevier
Objective Inflammatory bowel disease (IBD) is associated with anxiety and depression, but
the magnitude and directionality of risk remains uncertain. This study quantifies the risk of …

[HTML][HTML] Inflammatory bowel diseases, interleukin-6 and interleukin-6 receptor subunit alpha in causal association with cerebral cortical structure: a Mendelian …

C Liu, S Zhu, J Zhang, K Ren, K Li, J Yu - Frontiers in Immunology, 2023 - frontiersin.org
Background Neurological involvement and psychiatric manifestations have been
documented in clinical cases of inflammatory bowel disease (IBD); however, the presence of …