The role of small GTPases in neuronal morphogenesis and polarity
C Gonzalez‐Billault, P Muñoz‐Llancao… - …, 2012 - Wiley Online Library
The highly dynamic remodeling and cross talk of the microtubule and actin cytoskeleton
support neuronal morphogenesis. Small RhoGTPases family members have emerged as …
support neuronal morphogenesis. Small RhoGTPases family members have emerged as …
Direct modulation of small GTPase activity and function
PM Cromm, J Spiegel, TN Grossmann… - Angewandte Chemie …, 2015 - Wiley Online Library
Small GTPases are a family of GDP‐/GTP‐binding proteins that serve as biomolecular
switches inside cells to control a variety of essential cellular processes. Aberrant function …
switches inside cells to control a variety of essential cellular processes. Aberrant function …
The Cytotoxic Necrotizing Factor of Yersinia pseudotuberculosis (CNFY) Enhances Inflammation and Yop Delivery during Infection by Activation of Rho GTPases
J Schweer, D Kulkarni, A Kochut, J Pezoldt… - PLoS …, 2013 - journals.plos.org
Some isolates of Yersinia pseudotuberculosis produce the cytotoxic necrotizing factor
(CNFY), but the functional consequences of this toxin for host-pathogen interactions during …
(CNFY), but the functional consequences of this toxin for host-pathogen interactions during …
[HTML][HTML] C3 peptide promotes axonal regeneration and functional motor recovery after peripheral nerve injury
SC Huelsenbeck, A Rohrbeck, A Handreck… - …, 2012 - Elsevier
Peripheral nerve injuries are frequently seen in trauma patients and due to delayed nerve
repair, lifelong disabilities often follow this type of injury. Innovative therapies are needed to …
repair, lifelong disabilities often follow this type of injury. Innovative therapies are needed to …
Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGF
Cell chemotaxis, such as migration of fibroblasts towards growth factors during development
and wound healing, requires precise spatial coordination of signalling events …
and wound healing, requires precise spatial coordination of signalling events …
Inhibition of macrophage migration by C. botulinum exoenzyme C3
J Rotsch, A Rohrbeck, M May, T Kolbe… - Naunyn-Schmiedeberg's …, 2012 - Springer
C3-like exoenzymes are produced by various microorganism including Clostridium
botulinum (C3bot), Bacillus cereus and Staphylococcus aureus. C3bot is the prototype of C3 …
botulinum (C3bot), Bacillus cereus and Staphylococcus aureus. C3bot is the prototype of C3 …
Distinct biological activities of C3 and ADP‐ribosyltransferase‐deficient C3‐E174Q
A Rohrbeck, T Kolbe, S Hagemann, H Genth… - The FEBS …, 2012 - Wiley Online Library
Low‐molecular‐weight GTP‐binding proteins of the Rho family control the organization of
the actin cytoskeleton in eukaryotic cells. Dramatic reorganization of the actin cytoskeleton is …
the actin cytoskeleton in eukaryotic cells. Dramatic reorganization of the actin cytoskeleton is …
PKCα-mediated signals regulate the motile responses of cochlear outer hair cells
C Park, F Kalinec - Biophysical Journal, 2015 - cell.com
There is strong evidence that changes in the actin/spectrin-based cortical cytoskeleton of
outer hair cells (OHCs) regulate their motile responses as well as cochlear amplification, the …
outer hair cells (OHCs) regulate their motile responses as well as cochlear amplification, the …
Therapeutic effects of Clostridium botulinum C3 exoenzyme
I Just, A Rohrbeck, SC Huelsenbeck… - … Schmiedeberg's archives of …, 2011 - Springer
C3 exoenzyme from Clostridium botulinum, specifically ADP-ribosylates small GTP-binding
proteins RhoA, B, and C. ADP-ribosylation causes functional inactivation of Rho proteins …
proteins RhoA, B, and C. ADP-ribosylation causes functional inactivation of Rho proteins …
Direkte Modulation von Aktivität und Funktion kleiner GTPasen
PM Cromm, J Spiegel, TN Grossmann… - Angewandte …, 2015 - Wiley Online Library
Abstract Kleine GTPasen bilden eine Familie von GDP‐/GTP‐bindenden Proteinen, die als
biomolekulare Schalter innerhalb von Zellen wirken. Fehlfunktionen oder Fehlregulierungen …
biomolekulare Schalter innerhalb von Zellen wirken. Fehlfunktionen oder Fehlregulierungen …