The highly dynamic remodeling and cross talk of the microtubule and actin cytoskeleton
support neuronal morphogenesis. Small RhoGTPases family members have emerged as …

Small GTPases are a family of GDP‐/GTP‐binding proteins that serve as biomolecular
switches inside cells to control a variety of essential cellular processes. Aberrant function …

Some isolates of Yersinia pseudotuberculosis produce the cytotoxic necrotizing factor
(CNFY), but the functional consequences of this toxin for host-pathogen interactions during …

Peripheral nerve injuries are frequently seen in trauma patients and due to delayed nerve
repair, lifelong disabilities often follow this type of injury. Innovative therapies are needed to …

Cell chemotaxis, such as migration of fibroblasts towards growth factors during development
and wound healing, requires precise spatial coordination of signalling events …

C3-like exoenzymes are produced by various microorganism including Clostridium
botulinum (C3bot), Bacillus cereus and Staphylococcus aureus. C3bot is the prototype of C3 …

Low‐molecular‐weight GTP‐binding proteins of the Rho family control the organization of
the actin cytoskeleton in eukaryotic cells. Dramatic reorganization of the actin cytoskeleton is …

There is strong evidence that changes in the actin/spectrin-based cortical cytoskeleton of
outer hair cells (OHCs) regulate their motile responses as well as cochlear amplification, the …

C3 exoenzyme from Clostridium botulinum, specifically ADP-ribosylates small GTP-binding
proteins RhoA, B, and C. ADP-ribosylation causes functional inactivation of Rho proteins …

Abstract Kleine GTPasen bilden eine Familie von GDP‐/GTP‐bindenden Proteinen, die als
biomolekulare Schalter innerhalb von Zellen wirken. Fehlfunktionen oder Fehlregulierungen …