Abstract Serotonin (5-hydroxytrympamine or 5-HT) is one of the phylogenetically oldest
neurotransmitters, and the serotonergic system is among the earliest developed neuronal …

In the central nervous system (CNS), dopamine (DA) is involved in motor and cognitive
functions. Although the cerebellum is not been considered an elective dopaminergic region …

Disruption of the microbiota–gut–brain axis results in a wide range of pathologies that are
affected, from the brain to the intestine. Gut hormones released by enteroendocrine cells to …

The Human Proteome Project (HPP) aims to discover high-stringency data for all proteins
encoded by the human genome. Currently,∼ 18% of the proteins in the human proteome …

The regional and cellular distribution of serotonin type 2C receptor messenger RNA was
investigated in autopsy samples of human brain by in situ hybridization histochemistry. The …

This review article gives an overview of a number of central neuro-transmitters, which are
essential for integrating many functions in the central nervous system (CNS), such as …

The 5-ht5A receptor is enigmatic among 5-HT receptors since, although the human receptor
was cloned in 1994, until recently, very little has been learnt about the function of the …

Synaptic receptors in the human brain consist of multiple protein subunits, many of which
have multiple variants, coded by different genes, and are differentially expressed across …

Newborn neurons enter an extended maturation stage, during which they acquire excitability
characteristics crucial for development of presynaptic and postsynaptic connectivity. In …

Abstract Serotonin (5-HT) participates in pain modulation by interacting with different 5-HT
receptors. The role of 5-HT 5A receptor in neuropathic pain has not previously studied. The …