Worldwide, obesity is one of the most diffused pathologies. Several lines of recent evidence
link obesity with a higher risk of neurological pathologies such as anxiety and depression; …

Despite the human 5-HT5A receptor being cloned in 1994, the biological function of this
receptor has not been extensively characterized due to a lack of specific ligands. We …

A diagnosis of Alzheimer's disease is one of the most devastating things one can hear. This
terrible disease robs people of their ability to remember cherished events as their brains …

The nucleus tractus solitarus (NTS) integrates afferent information to maintain
cardiovascular homeostasis. Pharmacological experiments have indicated that 5-HT is …

Hydroxytryptamine (5-HT), also known as serotonin, is a small molecule synthesized from
tryptophan. The serotonergic cells project their axons to a large proportion of neurons, which …

The modified dopamine (DA) hypothesis of schizophrenia suggests a hyperdopaminergic
state in subcortical brain regions, which is believed to cause positive symptoms, while …

Neuromodulators have the capacity to alter neuronal excitability and synaptic strengths
throughout the nervous system, allowing animals to switch between different behavioral …

Abstract Serotonin (5-hydroxytryptamine, 5-HT) is a common neurotransmitter in mammals,
and the serotonergic system plays an essential role in the regulation of various behaviours …

Central 5-HT containing pathways have been shown to play an important role in the control
of micturition with a focus on 5-HT receptor influence on the parasympathetic outflow to the …

When I enrolled in the Medical School of Medicine in Pisa (Italy) I had no idea just what type
of doctor I wished to become; I was interested in the human being as a whole and not in …