[HTML][HTML] Are chemical compounds in medical mushrooms potent against colorectal cancer carcinogenesis and antimicrobial growth?

JM Macharia, L Zhang, RW Mwangi, N Rozmann… - Cancer Cell …, 2022 - Springer
After cardiovascular diseases, cancer is the second main cause of death globally.
Mushrooms have been demonstrated to contain amalgamation with properties capable of …

Colorectal cancer management: strategies in drug delivery

P Singh, P Waghambare, TA Khan… - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the third most common cancer leading to death
worldwide following breast and lung cancer with the incidence rate of 10%. The treatment …

A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer

X Liu, J Wu, D Zhang, K Wang, X Duan… - Evidence‐Based …, 2018 - Wiley Online Library
Background. As one of the most frequently diagnosed cancer diseases globally, colorectal
cancer (CRC) remains an important cause of cancer‐related death. Although the traditional …

[HTML][HTML] Notch signaling pathway dampens tumor-infiltrating CD8+ T cells activity in patients with colorectal carcinoma

W Yu, Y Wang, P Guo - Biomedicine & Pharmacotherapy, 2018 - Elsevier
CD8+ T cells play critical role in controlling the metastasis and prognosis of cancer.
Controversy remains as to the contribution of Notch signaling pathway in modulation of …

[HTML][HTML] A systematic review of selected plants and their metabolites with anticolorectal cancer effects

JM Macharia, RW Mwangi, N Rozmann, IN Wagara… - Phytomedicine Plus, 2022 - Elsevier
Background Colorectal cancer is among the most common malignancy and the third prime
cause of cancer-associated mortalities. Long-term inflammation of the colon can promote …

Network pharmacology interpretation of fuzheng–jiedu decoction against colorectal cancer

H Shi, S Tian, H Tian - Evidence‐Based Complementary and …, 2021 - Wiley Online Library
Introduction. Traditional Chinese medicine (TCM) believes that the pathogenic factors of
colorectal cancer (CRC) are “deficiency, dampness, stasis, and toxin,” and Fuzheng–Jiedu …

[HTML][HTML] A network pharmacology-based investigation on the bioactive ingredients and molecular mechanisms of Gelsemium elegans Benth against colorectal cancer

W Que, M Chen, L Yang, B Zhang, Z Zhao… - … Medicine and Therapies, 2021 - Springer
Background Colorectal cancer (CRC) remains one of the leading causes of cancer-related
death worldwide. Gelsemium elegans Benth (GEB) is a traditional Chinese medicine …

Sini decoction inhibits tumor progression and enhances the anti-tumor immune response in a murine model of colon cancer

J Chen, X Zheng, G Xu, B Wang, L Hu… - … Chemistry & High …, 2023 - ingentaconnect.com
Background: Sini decoction (SND) is a widely used Traditional Chinese Medicine (TCM).
The reports of SND application in colorectal cancer (CRC) is limited. Objective: The …

[HTML][HTML] D-Dimer level was associated with prognosis in metastatic colorectal cancer: A Chinese patients based cohort study

C Liu, Y Ning, X Chen, Q Zhu - Medicine, 2020 - journals.lww.com
D-dimer level is a direct measure of activated coagulation and has been used as a
biomarker of hypercoagulability. In this study, we aimed to explore the associations between …

Physiologically based pharmacokinetic modeling for prediction of 5-FU pharmacokinetics in cancer patients with hepatic impairment after 5-FU and capecitabine …

Y Wang, H Hu, L Yu, S Zeng - Pharmaceutical Research, 2023 - Springer
Abstract Purpose 5-fluorouracil (5-FU) and its prodrug capecitabine are commonly
prescribed anti-tumor medications. We aimed to establish physiologically based …