The physiology, signaling, and pharmacology of dopamine receptors
JM Beaulieu, RR Gainetdinov - Pharmacological reviews, 2011 - ASPET
G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …
Dopamine targeting drugs for the treatment of schizophrenia: past, present and future
P Li, GL Snyder, KE Vanover - Current topics in medicinal …, 2016 - ingentaconnect.com
Schizophrenia is a chronic and debilitating neuropsychiatric disorder affecting
approximately 1% of the world's population. This disease is associated with considerable …
approximately 1% of the world's population. This disease is associated with considerable …
Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents
S Miyamoto, N Miyake, LF Jarskog… - Molecular …, 2012 - nature.com
Since the introduction of chlorpromazine and throughout the development of the new-
generation antipsychotic drugs (APDs) beginning with clozapine, the D 2 receptor has been …
generation antipsychotic drugs (APDs) beginning with clozapine, the D 2 receptor has been …
Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II
SF Zhou - Clinical pharmacokinetics, 2009 - Springer
Part I of this article discussed the potential functional importance of genetic mutations and
alleles of the human cytochrome P450 2D6 (CYP2D6) gene. The impact of CYP2D6 …
alleles of the human cytochrome P450 2D6 (CYP2D6) gene. The impact of CYP2D6 …
Effects of prenatal infection on brain development and behavior: a review of findings from animal models
P Boksa - Brain, behavior, and immunity, 2010 - Elsevier
Epidemiological studies with human populations indicate associations between maternal
infection during pregnancy and increased risk in offspring for central nervous system (CNS) …
infection during pregnancy and increased risk in offspring for central nervous system (CNS) …
General anesthesia and altered states of arousal: a systems neuroscience analysis
EN Brown, PL Purdon… - Annual review of …, 2011 - annualreviews.org
Placing a patient in a state of general anesthesia is crucial for safely and humanely
performing most surgical and many nonsurgical procedures. How anesthetic drugs create …
performing most surgical and many nonsurgical procedures. How anesthetic drugs create …
Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology
TRE Barnes… - Journal of …, 2011 - journals.sagepub.com
These guidelines from the British Association for Psychopharmacology address the scope
and targets of pharmacological treatment for schizophrenia. A consensus meeting, involving …
and targets of pharmacological treatment for schizophrenia. A consensus meeting, involving …
A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development
The allostatic load (AL) model represents an interdisciplinary approach to comprehensively
conceptualize and quantify chronic stress in relation to pathologies throughout the life cycle …
conceptualize and quantify chronic stress in relation to pathologies throughout the life cycle …
Antipsychotic drugs: from receptor-binding profiles to metabolic side effects
Background: Antipsychotic-induced metabolic side effects are major concerns in
psychopharmacology and clinical psychiatry. Their pathogenetic mechanisms are still not …
psychopharmacology and clinical psychiatry. Their pathogenetic mechanisms are still not …
Short-term effects of antipsychotic treatment on cerebral function in drug-naive first-episode schizophrenia revealed by “resting state” functional magnetic resonance …
S Lui, T Li, W Deng, L Jiang, Q Wu… - Archives of general …, 2010 - jamanetwork.com
Context Most of what we know about antipsychotic drug effects is at the receptor level, distal
from the neural system effects that mediate their clinical efficacy. Studying cerebral function …
from the neural system effects that mediate their clinical efficacy. Studying cerebral function …