Chemokines are an indispensable component of our immune system through the regulation
of directional migration and activation of leukocytes. CXCL8 is the most potent human …

Over the past thirty years, the importance of chemokines and their seven-transmembrane G
protein-coupled receptors (GPCRs) has been increasingly recognized. Chemokine …

Inflammation is the body's defense response to exogenous or endogenous stimuli, involving
complex regulatory mechanisms. Discovering anti‐inflammatory drugs with both …

Background The impact of inflammatory factors on the development of Ankylosing
Spondylitis (AS) is widely recognized, but the exact causal relationship remains unclear …

Simple Summary Chronic inflammatory arthritis, such as rheumatoid arthritis (RA) and
spondyloarthritis (SpA), often have a significant impact on bone tissue, where bone is not …

Ankylosing spondylitis (AS) is a rheumatic bone and joint disease caused by inflammation,
erosion, and pathological bone formation. The pathological features of chronic inflammation …

Qualitative alterations in type I collagen due to pathogenic variants in the COL1A1 or
COL1A2 genes, result in moderate and severe Osteogenesis Imperfecta (OI), a rare disease …

Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease that mainly affects
the axial skeleton, whose typical features are inflammatory back pain, bone structural …

Injectable hydrogels, offering adaptable drug delivery of growth factors (GFs), hold promise
for treating bone defects. To optimize osteogenic efficacy, the release of GFs should mirror …

Stress-induced premature senescent (SIPS) cells induced by various stresses deteriorate
cell functions. Dasatinib and quercetin senolytics (DQ) can alleviate several diseases by …