Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress

A Slominski, J Wortsman, T Luger… - Physiological …, 2000 - journals.physiology.org
The skin is a known target organ for the proopiomelanocortin (POMC)-derived
neuropeptides α-melanocyte stimulating hormone (α-MSH), β-endorphin, and ACTH and …

Endocrinology of human parturition

S Vannuccini, C Bocchi, FM Severi, JR Challis… - Annales d' …, 2016 - Elsevier
The mechanisms involved in human pregnancy maintenance and parturition are highly
complex and involve mother, fetus and placenta. The “final common pathway” to delivery is …

Corticotropin releasing factor receptors and their ligand family

MH Perrin, WW Vale - Annals of the New York Academy of …, 1999 - Wiley Online Library
The CRF receptors belong to the VIP/GRF/PTH family of G‐protein coupled receptors whose
actions are mediated through activation of adenylate cyclase. Two CRF receptors, encoded …

Neuroendocrine mechanisms in pregnancy and parturition

F Petraglia, A Imperatore, JRG Challis - Endocrine reviews, 2010 - academic.oup.com
The complex mechanisms controlling human parturition involves mother, fetus, and
placenta, and stress is a key element activating a series of physiological adaptive …

Urocortin expression in rat brain: evidence against a pervasive relationship of urocortin‐containing projections with targets bearing type 2 CRF receptors

JC Bittencourt, J Vaughan, C Arias… - Journal of …, 1999 - Wiley Online Library
Histochemical and axonal transport methods were used to clarify the central organization of
cells and fibers that express urocortin (UCN), a recently discovered corticotropin‐releasing …

Cutaneous expression of corticotropin‐releasing hormone (CRH), urocortin, and CRH receptors

A SLOMINSKI, J WORTSMAN, A PISARCHIK… - The FASEB …, 2001 - Wiley Online Library
Studies in mammalian skin have shown expression of the genes for corticotropin‐releasing
hormone (CRH) and the related urocortin peptide, with subsequent production of the …

Physiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs

ÉM Fekete, EP Zorrilla - Frontiers in neuroendocrinology, 2007 - Elsevier
Urocortins, three paralogs of the stress-related peptide corticotropin-releasing factor (CRF)
found in bony fish, amphibians, birds, and mammals, have unique phylogenies …

Nesfatin-1 exerts a direct, glucose-dependent insulinotropic action on mouse islet β-and MIN6 cells

R Gonzalez, BK Reingold, X Gao… - Journal of …, 2011 - joe.bioscientifica.com
Nesfatin-1 is a recently discovered multifunctional metabolic hormone abundantly
expressed in the pancreatic islets. The main objective of this study is to characterize the …

Urocortin protects against ischemic and reperfusion injury via a MAPK-dependent pathway

BK Brar, AK Jonassen, A Stephanou, G Santilli… - Journal of Biological …, 2000 - ASBMB
Urocortin (UCN) is a peptide related to hypothalamic corticotrophin-releasing hormone and
binds with high affinity to corticotrophin-releasing hormone receptor-2β, which is expressed …

Periconceptional undernutrition in sheep accelerates maturation of the fetal hypothalamic-pituitary-adrenal axis in late gestation

FH Bloomfield, MH Oliver, P Hawkins… - …, 2004 - academic.oup.com
We investigated the effects of moderate maternal periconceptional undernutrition from 60 d
before to 30 d after mating on fetal hypothalamic-pituitary-adrenal axis function in late …