BACKGROUND Infertility is an important side effect of treatments used for cancer and other
non-malignant conditions in males. This may be due to the loss of spermatogonial stem cells …

BACKGROUND Germ cell depletion caused by chemical or physical toxicity, disease or
genetic predisposition can occur at any age. Although semen cryopreservation is the first …

Patients preparing to undergo gonadotoxic medical therapy, radiation therapy, or
gonadectomy should be provided with prompt counseling regarding available options for …

STUDY QUESTION Is it feasible to disseminate testicular tissue cryopreservation with a
standardized protocol through a coordinated network of centers and provide centralized …

Aim To provide practice guidelines about fertility preservation (FP) in oncology. Methods We
selected 400 articles after a PubMed review of the literature (1987–2019) …

BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …

Medical treatments for cancers or other conditions can lead to permanent infertility. Infertility
is an insidious disease that impacts not only the ability to have a biological child but also the …

Due to the growing number of young patients at risk of germ cell loss, there is a need to
preserve spermatogonial stem cells for patients who are not able to bank spermatozoa …

STUDY QUESTION What is the long-term reproductive health outcome of patients who have
undergone testicular sampling for fertility preservation (FP) before and during the pubertal …

Many cancers presenting in children and adolescents are curable with surgery,
chemotherapy, and/or radiotherapy. Potential adverse consequences of treatment include …