Young boys undergoing gonadotoxic treatments are at high risk of spermatogonial stem cell
(SSC) loss and fertility problems later in life. Stem cell loss can also occur in specific genetic …

Objective To collect published data on spermatogonial quantity in the testes of healthy
children and calculate the reference values of spermatogonial quantities throughout …

Background Few studies have reported the long‐term outcomes of prepubertal and pubertal
boys undergoing testicular biopsy for fertility preservation (FP). Procedure This prospective …

The broad conceptualization of fertility preservation and restoration has become already a
major concern in the modern western world since a large number of individuals often face it …

Fertility preservation in prepubertal boys is a matter that has been gaining ground fast during
the past 20 years. As the life expectancy for childhood cancer survivors continues to …

While the survival rate of children with cancer is increasing, preserving fertility for
prepubertal boys is still a challenge. Although intracytoplasmic sperm injection (ICSI) using …

Advancements in cancer therapies over the past several decades have led to a rise in
pediatric cancer survival rates to approximately 88%. 1 This increase in cancer survivorship …

An increasing number of men require long-term drug therapy for various diseases. However,
the effects of long-term drug therapy on male fertility are often not well evaluated in clinical …

Transplantation of testicular tissues and cells has been proposed as a future clinical option
for patients who have had testicular tissue cryopreserved prior to receiving gonadotoxic …

Background The lifesaving chemotherapy and radiation treatments that allow patients to
survive cancer can also result in a lifetime of side-effects, including male infertility. Infertility …