Testicular tissue cryopreservation is the only fertility preservation option available to
prepubertal boys who are not able to cryopreserve a semen sample with sperm. Published …

Young boys undergoing gonadotoxic treatments are at high risk of SSC loss and fertility
problems later in life. Stem cell loss can also occur in specific genetic conditions, eg, KS …

Antineoplastic treatments improve the life expectancy of pediatric cancer patients, but may
result in male infertility by ablating spermatogonial stem cells (SSCs). Cryopreservation of …

The latest progress in therapies indicated for the treatment of childhood cancers has
enabled the improvement of survival rates in affected patients. However, the treatment can …

Testis-derived spermatogonial stem cells (SSCs) and its in vitro counterpart, male germline
stem (GS) cells, can repopulate the empty seminiferous tubules of infertile males and …

Survival rates after cancer treatment have increased dramatically in recent decades,
resulting in an increasing focus on the harmful effects of cancer treatment for these patients …

Several conditions can affect men's reproductive capacity during their lifespan such as
gonadotoxic treatments for oncological diseases [1] or for benign hematological diseases …

This review highlights some of the aspects of the fertility in patients with germ cell tumors.
This problem appears to be the very actual problem because of the possible impact not only …

Infertility due to exposure to chemotherapy and radiation has a detrimental effect of the
patient's quality of life. A number of spermatogonial stem cell (SSC)-based methods are …

Wider implications: Fertility restoration techniques are very promising and expected to be
implemented in the clinic in the near future. However, inter-center variability needs to be …