Diversity of malignancies in patients with different types of inborn errors of immunity
Genetic defects in the development, maturation, and/or function of the immune cells can lead
to Inborn errors of immunity (IEI) which may predispose patients to malignancies. The overall …
to Inborn errors of immunity (IEI) which may predispose patients to malignancies. The overall …
Predominantly antibody deficiencies
Primary antibody deficiencies (PADs) are frequent primary immunodeficiencies in humans,
characterized by hypogammaglobulinemia, defects in production of specific antibodies, and …
characterized by hypogammaglobulinemia, defects in production of specific antibodies, and …
New Presentation of CD27 Deficiency; Coronary Ectasia and COVID-19
Z Golchehre, S Sharafian… - Iranian Journal of …, 2023 - ijaai.tums.ac.ir
CD27 is a costimulatory receptor involved in the maturation of the innate and adaptive
immunity. CD27, through interaction with CD70, plays a role in the control of Epstein-Barr …
immunity. CD27, through interaction with CD70, plays a role in the control of Epstein-Barr …
Cutaneous granulomatosis and class switching defect as a presenting sign in ataxia-telangiectasia: first case from the national Iranian registry and review of the …
Ataxia-telangiectasia (AT) is a rare autosomal recessive syndrome characterized by
progressive cerebellar ataxia, oculocutaneous telangiectasia, immunodeficiency and cancer …
progressive cerebellar ataxia, oculocutaneous telangiectasia, immunodeficiency and cancer …
A new case of congenital ficolin-3 deficiency with primary immunodeficiency
F Babaha, H Abolhassani… - Expert Review of …, 2020 - Taylor & Francis
ABSTRACT Objectives Human Ficolin-3 (FCN3) is an oligomeric-structured lectin encoded
by the FCN3 gene with a pivotal role in the lectin complement pathway. It has anti-microbial …
by the FCN3 gene with a pivotal role in the lectin complement pathway. It has anti-microbial …
Respiratory complications in patients with hyper IgM syndrome
Abstract Purpose Hyper Immunoglobulin M (HIgM) syndrome is a heterogeneous group of
primary immunodeficiency disorders, characterized by recurrent infections and associated …
primary immunodeficiency disorders, characterized by recurrent infections and associated …
Evaluation of expression of LRBA and CTLA-4 proteins in common variable immunodeficiency patients
Common variable immunodeficiency (CVID) is a primary immunodeficiency disease with a
heterogeneous genetic background. Lipopolysaccharide-responsive beige-like anchor …
heterogeneous genetic background. Lipopolysaccharide-responsive beige-like anchor …
Autoimmune manifestations among 461 patients with monogenic inborn errors of immunity
Background The inborn errors of immunity (IEIs) are a group of heterogeneous disorders
mainly characterized by severe and recurrent infections besides other complications …
mainly characterized by severe and recurrent infections besides other complications …
Autoimmune versus Non-autoimmune Cutaneous Features in Monogenic Patients with Inborn Errors of Immunity
Simple Summary Cutaneous manifestations were observed in~ 44% of Iranian patients with
monogenic IEI. A considerable number of these patients developed cutaneous disorders as …
monogenic IEI. A considerable number of these patients developed cutaneous disorders as …
Inborn Errors of Immunity in Jordan: First Report from a Tertiary Referral Center
R Alzyoud, M Alsuweiti, H Maaitah, B Aladaileh… - Journal of Clinical …, 2024 - Springer
Purpose Inborn errors of immunity (IEI) are a heterogeneous group of diseases with variable
clinical phenotypes. This study was conducted to describe the epidemiology, clinical …
clinical phenotypes. This study was conducted to describe the epidemiology, clinical …