Cardiac ablation with pulsed electric fields: principles and biophysics

A Sugrue, E Maor, F Del-Carpio Munoz, AM Killu… - Europace, 2022 - academic.oup.com
Pulsed electric fields (PEFs) have emerged as an ideal cardiac ablation modality. At present
numerous clinical trials in humans are exploring PEF as an ablation strategy for both atrial …

Image-guided ablation for colorectal liver metastasis: principles, current evidence, and the path forward

YM Lin, I Paolucci, KK Brock, BC Odisio - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer is the fourth most common type of cancer globally.
Approximately 20% of patients with colorectal cancer present with synchronous liver …

Image-guided tumor ablation: standardization of terminology and reporting criteria—a 10-year update

M Ahmed, L Solbiati, CL Brace, DJ Breen… - Radiology, 2014 - pubs.rsna.org
Image-guided tumor ablation has become a well-established hallmark of local cancer
therapy. The breadth of options available in this growing field increases the need for …

Irreversible electroporation ablation: is all the damage nonthermal?

M Faroja, M Ahmed, L Appelbaum, E Ben-David… - Radiology, 2013 - pubs.rsna.org
Purpose To determine whether high-dose irreversible electroporation (IRE) ablation induces
thermal effects in normal liver tissue. Materials and Methods Animal care and use committee …

A numerical investigation of the electric and thermal cell kill distributions in electroporation-based therapies in tissue

PA Garcia, RV Davalos, D Miklavcic - PloS one, 2014 - journals.plos.org
Electroporation-based therapies are powerful biotechnological tools for enhancing the
delivery of exogeneous agents or killing tissue with pulsed electric fields (PEFs) …

Safety and efficacy of irreversible electroporation for the treatment of hepatocellular carcinoma not amenable to thermal ablation techniques: a retrospective single …

O Sutter, J Calvo, G N'kontchou, JC Nault, R Ourabia… - Radiology, 2017 - pubs.rsna.org
Purpose To assess the safety and efficacy of irreversible electroporation (IRE) in the
treatment of patients with inoperable hepatocellular carcinoma (HCC) who are ineligible for …

Integration of very short electric pulses for minimally to noninvasive electroporation

R Davalos, B Christopher, J Caldwell - US Patent 8,926,606, 2015 - Google Patents
The present invention provides methods, devices, and sys tems for in vivo treatment of cell
proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors …

Irreversible electroporation versus radiofrequency ablation: a comparison of local and systemic effects in a small-animal model

BE Bulvik, N Rozenblum, S Gourevich, M Ahmed… - Radiology, 2016 - pubs.rsna.org
Purpose To compare both periablational and systemic effects of two mechanistically different
types of ablation: thermal radiofrequency (RF) ablation and electroporative ablation with …

Treatment planning for electroporation-based therapies

IIRE Neal, PA Garcia, RV Davalos… - US Patent …, 2015 - Google Patents
2011-04-27 Assigned to VIRGINIA TECH INTELLECTUAL PROPERTIES, INC.
reassignment VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. ASSIGNMENT OF …

Irreversible electroporation: treatment effect is susceptible to local environment and tissue properties

E Ben-David, M Ahmed, M Faroja, M Moussa… - Radiology, 2013 - pubs.rsna.org
Purpose To study the effects of the surrounding electrical microenvironment and local tissue
parameters on the electrical parameters and outcome of irreversible electroporation (IRE) …