Epithelial growth factor receptor (EGFR), a transmembrane receptor on the cell surface,
carries extracellular messages into the cell and alters the activity of the nucleus through …

Nano-drug delivery systems have opened new pathways for tumor treatment by overcoming
some of the limitations of conventional drugs, such as physiological degradation, short half …

Gefitinib (GEF) is utilized in clinical settings for the treatment of metastatic lung cancer.
However, premature drug release from nanoparticles in vivo increases the exposure of …

ABSTRACT According to the World Health Organization (WHO), cancer is the second-
highest cause of mortality worldwide, killing nearly 9.6 million people annually. Despite the …

Lung cancer is a formidable challenge in clinical practice owing to its metastatic nature and
resistance to conventional treatments. The codelivery of anticancer agents offers a potential …

In this work, a tumor-targeting liposome containing anti-nucleolin aptamer AS1411 (Apt-Lip-
GEF) was developed to deliver gefitinib (GEF) for the treatment of colon cancer. The …

Nanotechnology has expanded in drug delivery applications in recent years due to inherent
features such as drug compatibility, improved solubility/bioavailability of poorly soluble …

Aim: This study aimed to improve the delivery and therapeutic potential of gefitinib (GTB)
against breast cancer by preparing GTB-loaded, nanostructured lipid carriers (GTB-NLCs) …

To employ crystal engineering for the design and synthesis of a series of novel
salts/cocrystals incorporating phenolic acids, aiming to modulate the solubility of gefitinib …

Background The present study revealed the grafting of extracted oleo gum resin of Boswellia
serrata with polyacrylamide by conventional method with a principle of radical …