Background Cognitive impairment, a defining feature of dementia, plays an important role in
the compromised functional independence that characterises the condition. Cognitive …

The classical studies of nicotine by Langley at the turn of the 20th century introduced the
concept of a “receptive substance,” from which the idea of a “receptor” came to light …

Background Cognitive impairments, particularly memory problems, are a defining feature of
the early stages of Alzheimer's disease (AD) and vascular dementia. Cognitive training and …

Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are constructed from
numerous subunit combinations that compose channel-receptor complexes with varied …

Alzheimer's disease (AD) is the most common neurodegenerative disorder and the most
prevalent cause of dementia with ageing. Pharmacological treatment of AD is based on the …

Memory difficulties are a defining feature of Alzheimer's disease (AD), with significant
implications for people with AD and family members. Interventions aimed at helping with …

20 Comparison 05. Cognitive training (intensive home practice) vs dyadic counselling at 8
weeks........ 21 Comparison 06. Cognitive training (intensive home practice) vs dual …

Almost all degenerative diseases of the CNS are associated with chronic inflammation. A
central step in this process is the activation of brain mononuclear phagocyte cells, called …

Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand gated ion
channels which are widely distributed in the human brain. Multiple subtypes of these …

Cognitive impairments, and particularly memory deficits, are a defining feature of the early
stages of Alzheimer's disease and vascular dementia. Interventions that target these …