Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
1 to 3% of individuals over the age of 65 years. While effective therapy exists for treating the …

The multiple combinations of nAChR subunits identified in central nervous structures posses
distinct pharmacological and physiological properties. A growing number of data have …

Several epidemiological studies have shown that cigarette smoking might alter the
incidence of Alzheimer's disease. However, inconsistent results have been reported …

Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder and the most
common cause of dementia. The early stages of AD are characterized by short-term memory …

The aim of present study is to predict the probable nootropic activity of novel nicotine
analogues with the help of computer program, PASS (prediction of activity spectra for …

The hippocampus is a center for learning and memory that receives abundant cholinergic
innervation and richly expresses nicotinic acetylcholine receptors (nAChRs). Nicotinic …

Activation of the immune system and derangement of cardiorespiratory neural control are
established elements of the complex pathophysiology of chronic heart failure (CHF). The …

Substances such as acetylcholine and glutamate act as both neurotransmitters and
neuromodulators. As neuromodulators, they change neural information processing by …

In the present study, we have investigated the expression of nicotinic acetylcholine receptors
(nAChRs) on astrocytes and neurons in the hippocampus and temporal cortex of subjects …

The report focused on investigating the relationship between cigarette smoking and
dementia in elderly people through prospective studies. We did a 2‐year follow‐up study of …