Background: A review of the literature of the element fluorine and its bonded-form, fluoride,
was undertaken. Generally regarded as safe, an expanding body of literature reveals that …

Impaired cholinergic function in the central nervous system is an early feature of Alzheimer
disease (AD). Currently, cholinergic deficit is usually corrected by increasing the amount of …

In case-control studies using prevalent cases, an apparent association may be spurious if
the risk factor affects survival. In his description of this potential bias, Neyman disregarded …

The present report describes the participation of nicotinic receptors (nAChRs) in controlling
the excitability of local neuronal circuitries in the rat hippocampus and in the human cerebral …

Nicotinic systems play an important role in the neural basis of working memory and
attention. Recent progress in understanding of the structure, function, and distribution of …

Age-related hearing loss is a complex disorder affecting a majority of the elderly population.
As people age, speech understanding becomes a challenge especially in complex acoustic …

Epidemiological studies have reported that cigarette smoking may protect from
neurodegenerative diseases such as Parkinson's disease. These protective effects are …

An individual, goal-oriented cognitive rehabilitation intervention was conducted with AB, a
77-year-old woman with MCI. Outcomes were evaluated using a client-centred measure of …

Agonists of the a4b2 nicotinic acetylcholine receptors have been synthesised as potential
drugs for treatment of a variety of diseases. In this review, the published nicotinic agonists …

Various active compounds derived primarily from Oriental and European medicinal plants,
including Ginkgo biloba, Panax ginseng, Nicotiana tobaccum, Huperzia serrata, Galanthus …