Exosomal PD-L1 derived from head and neck squamous cell carcinoma promotes immune evasion by activating the positive feedback loop of activated regulatory T …
F Wei, R Fang, K Lyu, J Liao, Y Long, J Yang, W Wen… - Oral Oncology, 2023 - Elsevier
The positive feedback loop of activated regulatory T cells (aTregs) and M2 macrophages
(M2) play a vital role in promoting the tumor immunosuppressive microenvironment of head …
(M2) play a vital role in promoting the tumor immunosuppressive microenvironment of head …
Smart nanomaterials as the foundation of a combination approach for efficient cancer theranostics
Despite numerous FDA-approved treatment and diagnostic approaches, cancer is one of the
leading causes of death worldwide due to delayed diagnostics and the limited efficacy of …
leading causes of death worldwide due to delayed diagnostics and the limited efficacy of …
[PDF][PDF] Biomarkers for immunotherapy of oral squamous cell carcinoma: current status and challenges
A Almangush, I Leivo, AA Mäkitie - Frontiers in oncology, 2021 - frontiersin.org
Oral squamous cell carcinoma (OSCC) forms a major health problem in many countries. For
several decades the management of OSCC consisted of surgery with or without …
several decades the management of OSCC consisted of surgery with or without …
[HTML][HTML] The role of matrix stiffness in cancer stromal cell fate and targeting therapeutic strategies
J Wei, J Yao, M Yan, Y Xie, P Liu, Y Mao, X Li - Acta Biomaterialia, 2022 - Elsevier
The tumor microenvironment (TME) is a complex macromolecular network filled with a series
of stromal cells. It plays an important role in tumorigenesis, development, immune escape …
of stromal cells. It plays an important role in tumorigenesis, development, immune escape …
Nanomaterials for cascade promoted catalytic cancer therapy
Z Tong, Y Gao, H Yang, W Wang, Z Mao - View, 2021 - Wiley Online Library
Catalytic therapy utilizing special substances (eg, hydrogen peroxide and glucose) in tumor
sites has attracted wide interest to achieve tumor‐specific therapy or improve the efficacy of …
sites has attracted wide interest to achieve tumor‐specific therapy or improve the efficacy of …
Catalytically Selective Chemotherapy from Tumor‐Metabolic Generated Lactic Acid
Z Tian, K Yang, T Yao, X Li, Y Ma, C Qu, X Qu, Y Xu… - Small, 2019 - Wiley Online Library
Lactic acid (LA) is a powerful molecule as the metabolic driver in tumor microenvironments
(TMEs). Inspired by its high intratumoral level (5–20 µmol g− 1), a novel treatment paradigm …
(TMEs). Inspired by its high intratumoral level (5–20 µmol g− 1), a novel treatment paradigm …
Long non-coding RNAs in the tumor immune microenvironment: biological properties and therapeutic potential
YN Pi, WC Qi, BR Xia, G Lou, WL Jin - Frontiers in immunology, 2021 - frontiersin.org
Cancer immunotherapy (CIT) is considered a revolutionary advance in the fight against
cancer. The complexity of the immune microenvironment determines the success or failure …
cancer. The complexity of the immune microenvironment determines the success or failure …
Nanofibers for the immunoregulation in biomedical applications
L Fu, Q Feng, Y Chen, J Fu, X Zhou, C He - Advanced Fiber Materials, 2022 - Springer
Despite great efforts and achievement of nanomaterials in immune-associated diseases, the
selection of appropriate nanomaterials and preparation technology remain some challenges …
selection of appropriate nanomaterials and preparation technology remain some challenges …
Viruses and bacteria associated with cancer: an overview
D Zella, RC Gallo - Viruses, 2021 - mdpi.com
There are several human viruses and bacteria currently known to be associated with cancer.
A common theme indicates that these microorganisms have evolved mechanisms to hamper …
A common theme indicates that these microorganisms have evolved mechanisms to hamper …
Intratumoral fate of functional nanoparticles in response to microenvironment factor: Implications on cancer diagnosis and therapy
The extraordinary growth and progression of tumor require enormous nutrient and energy.
Unregulated behaviors of cancer cell progressing and persistently change of tumor …
Unregulated behaviors of cancer cell progressing and persistently change of tumor …