Immune checkpoint inhibitors as mediators for immunosuppression by cancer-associated fibroblasts: A comprehensive review
F Eskandari-Malayeri, M Rezaei - Frontiers in Immunology, 2022 - frontiersin.org
The tumor microenvironment (TME) is a significant contributor to cancer progression
containing complex connections between cellular and chemical components and provides a …
containing complex connections between cellular and chemical components and provides a …
The multiple layers of the tumor environment
The notion of tumor microenvironment (TME) has been brought to the forefront of recent
scientific literature on cancer. However, there is no consensus on how to define and spatially …
scientific literature on cancer. However, there is no consensus on how to define and spatially …
Novel design of multifunctional nanozymes based on tumor microenvironment for diagnosis and therapy
X Zhu, N Xu, L Zhang, D Wang, P Zhang - European Journal of Medicinal …, 2022 - Elsevier
Nanozymes have entranced considerable concern since they provide a likelihood strategy
for performing the integration of diagnosis and therapy. Nanozymes, as emerging …
for performing the integration of diagnosis and therapy. Nanozymes, as emerging …
Immune cell infiltration signatures identified molecular subtypes and underlying mechanisms in gastric cancer
Y Lin, X Pan, L Zhao, C Yang, Z Zhang, B Wang… - NPJ Genomic …, 2021 - nature.com
Increasing evidence has clarified that the tumor microenvironment (TME) is closely related to
the prognosis and therapeutic efficacy of cancer. However, there is no reliable TME …
the prognosis and therapeutic efficacy of cancer. However, there is no reliable TME …
Single-cell transcriptome sequencing reveals heterogeneity of gastric cancer: progress and prospects
G Deng, X Zhang, Y Chen, S Liang, S Liu, Z Yu… - Frontiers in …, 2023 - frontiersin.org
Gastric cancer is one of the most serious malignant tumor and threatens the health of people
worldwide. Its heterogeneity leaves many clinical problems unsolved. To treat it effectively …
worldwide. Its heterogeneity leaves many clinical problems unsolved. To treat it effectively …
Three-dimensional 3D culture models in gynecological and breast cancer research
YM Salinas-Vera, J Valdes, Y Perez-Navarro… - Frontiers in …, 2022 - frontiersin.org
Traditional two-dimensional (2D) monolayer cell cultures have long been the gold standard
for cancer biology research. However, their ability to accurately reflect the molecular …
for cancer biology research. However, their ability to accurately reflect the molecular …
Recent advances in silver nanozymes: concept, mechanism, and applications in detection
Natural enzymes accelerate substrate‐specific reactions making them of exquisite interest
for various applications. However, their appeal is lost in a practical setting due to low stability …
for various applications. However, their appeal is lost in a practical setting due to low stability …
Chronic cancer pain: opioids within tumor microenvironment affect neuroinflammation, tumor and pain evolution
A Santoni, M Santoni, E Arcuri - Cancers, 2022 - mdpi.com
Simple Summary Pain is a worrisome symptom that 60–80% of patients with cancer
experience chronically. In the last twenty years, immunological and pain research have …
experience chronically. In the last twenty years, immunological and pain research have …
Clear‐Box Machine Learning for Virtual Screening of 2D Nanozymes to Target Tumor Hydrogen Peroxide
XJ Gao, J Yan, JJ Zheng, S Zhong… - Advanced Healthcare …, 2023 - Wiley Online Library
Targeting tumor hydrogen peroxide (H2O2) with catalytic materials has provided a novel
chemotherapy strategy against solid tumors. Because numerous materials have been …
chemotherapy strategy against solid tumors. Because numerous materials have been …
A covalent organic framework-based multifunctional therapeutic platform for enhanced photodynamic therapy via catalytic cascade reactions
Utilizing the unique tumor microenvironment (TME) to conduct chemical reactions for cancer
treatment becomes a hot topic recently. Nevertheless, single chemical reaction in TME is …
treatment becomes a hot topic recently. Nevertheless, single chemical reaction in TME is …