Contribution of PET imaging to radiotherapy planning and monitoring in glioma patients-a report of the PET/RANO group
N Galldiks, M Niyazi, AL Grosu, M Kocher… - Neuro …, 2021 - academic.oup.com
The management of patients with glioma usually requires multimodality treatment including
surgery, radiotherapy, and systemic therapy. Accurate neuroimaging plays a central role for …
surgery, radiotherapy, and systemic therapy. Accurate neuroimaging plays a central role for …
Recent advances of PET imaging in clinical radiation oncology
M Unterrainer, C Eze, H Ilhan, S Marschner… - Radiation …, 2020 - Springer
Radiotherapy and radiation oncology play a key role in the clinical management of patients
suffering from oncological diseases. In clinical routine, anatomic imaging such as contrast …
suffering from oncological diseases. In clinical routine, anatomic imaging such as contrast …
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases
X Xiang, K Wind, T Wiedemann, T Blume… - Science translational …, 2021 - science.org
2-Deoxy-2-[18F] fluoro-d-glucose positron emission tomography (FDG-PET) is widely used
to study cerebral glucose metabolism. Here, we investigated whether the FDG-PET signal is …
to study cerebral glucose metabolism. Here, we investigated whether the FDG-PET signal is …
PET imaging in neuro-oncology: An update and overview of a rapidly growing area
Simple Summary Positron emission tomography (PET) is a functional imaging technique
which plays an increasingly important role in the management of brain tumors. Owing …
which plays an increasingly important role in the management of brain tumors. Owing …
Opposite microglial activation stages upon loss of PGRN or TREM 2 result in reduced cerebral glucose metabolism
Microglia adopt numerous fates with homeostatic microglia (HM) and a microglial
neurodegenerative phenotype (MG nD) representing two opposite ends. A number of …
neurodegenerative phenotype (MG nD) representing two opposite ends. A number of …
Pan-vaccinomics approach towards a universal vaccine candidate against WHO priority pathogens to address growing global antibiotic resistance
Antimicrobial resistance (AMR) in bacterial pathogens is a major global distress. Due to the
slow progress of antibiotics development and the fast pace of resistance acquisition, there is …
slow progress of antibiotics development and the fast pace of resistance acquisition, there is …
The role of translocator protein TSPO in hallmarks of glioblastoma
Simple Summary The translocator protein (TSPO) has been under extensive investigation as
a specific marker in positron emission tomography (PET) to visualize brain lesions following …
a specific marker in positron emission tomography (PET) to visualize brain lesions following …
Translocator protein (18kDA)(TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages
L Weidner, J Lorenz, S Quach, FK Braun… - Acta Neuropathologica …, 2023 - Springer
TSPO is a promising novel tracer target for positron-emission tomography (PET) imaging of
brain tumors. However, due to the heterogeneity of cell populations that contribute to the …
brain tumors. However, due to the heterogeneity of cell populations that contribute to the …
Sifting through the surfeit of neuroinflammation tracers
The first phase of molecular brain imaging of microglial activation in neuroinflammatory
conditions began some 20 years ago with the introduction of [11C]-(R)-PK11195, the …
conditions began some 20 years ago with the introduction of [11C]-(R)-PK11195, the …
[HTML][HTML] A perspective on the radiopharmaceutical requirements for imaging and therapy of glioblastoma
J Bolcaen, J Kleynhans, S Nair, J Verhoeven… - Theranostics, 2021 - ncbi.nlm.nih.gov
Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …