Left atrial appendage exclusion for stroke prevention in patients with nonrheumatic atrial fibrillation

O Onalan, E Crystal - Stroke, 2007 - Am Heart Assoc
The efficacy of oral anticoagulation (OAC) for stroke prevention in patients with
nonrheumatic atrial fibrillation (AF) has clearly been established. However, a substantial …

Systems and methods of tissue closure

WK Wheeler, AA Mohan - US Patent 9,375,218, 2016 - Google Patents
Apparatus, systems, and methods are described for closing the base of a left atrial
appendage or other tissue structure. A tissue closure device comprises a pair of legs having …

Left atrial appendage occlusion: lessons learned from surgical and transcatheter experiences

S Chatterjee, JC Alexander, PJ Pearson… - The Annals of thoracic …, 2011 - Elsevier
Since the 1950s, the pathophysiologic role of the left atrial appendage (LAA) has been
known in thromboembolic disease. A variety of surgical techniques have been described to …

Success of surgical left atrial appendage closure: assessment by transesophageal echocardiography

AS Kanderian, AM Gillinov, GB Pettersson… - Journal of the American …, 2008 - jacc.org
Objectives: We sought to determine which surgical technique of left atrial appendage (LAA)
closure is most successful by assessing them with transesophageal echocardiography …

Occluding the left atrial appendage: anatomical considerations

P Su, KP Mccarthy, SY Ho - Heart, 2008 - heart.bmj.com
Background: Occlusion of the left atrial appendage (LAA) is thought to reduce the risk of
thromboembolic events in patients with atrial fibrillation. Objective: To examine the LAA and …

Tissue ligation devices and tensioning devices therefor

GW Fung, RD Helmuth, AM Escano, RA Seiber… - US Patent …, 2016 - Google Patents
Described here are closure devices and methods for ligating tissue, such as the left atrial
appendage, and tensioning devices and mechanism for actuating these devices. The …

Surgical closure of the left atrial appendage–a beneficial procedure?

B Schneider, C Stöllberger, HH Sievers - Cardiology, 2005 - karger.com
Background: Closure of the fibrillating left atrial appendage (LAA) has been recommended
during valve surgery to decrease the risk of arterial embolism. However, patients undergoing …

[PDF][PDF] Percutaneous left atrial appendage transcatheter occlusion (PLAATO) for stroke prevention in atrial fibrillation: 2-year outcomes

JW Park, B Leithauser, U Gerk… - Journal of Invasive …, 2009 - researchgate.net
Purpose. In more than 90% of patients with atrial fibrillation (AF), stroke is due to thrombotic
embolization from the left atrial appendage (LAA). Transcatheter occlusion with …

Metabolic effects of the left atrial appendage exclusion (the heart hormone study)

K Bartus, MA Elbey, SH Kanuri, R Lee… - Journal of …, 2022 - Wiley Online Library
Introduction The effect of epicardial left atrial appendage (LAA) occlusion therapy on lipid
and glucose metabolism in atrial fibrillation (AF) patients over the long‐term follow‐up are …

Nonpharmacologic stroke prevention in atrial fibrillation

O Onalan, I Lashevsky, A Hamad… - Expert review of …, 2005 - Taylor & Francis
Atrial fibrillation is associated with significant mortality and morbidity. The burden of
morbidity in atrial fibrillation is mostly due to stroke, one of the major causes of death and the …