Oral delivery of anticancer drugs III: formulation using drug delivery systems

S Mazzaferro, K Bouchemal, G Ponchel - Drug discovery today, 2013 - Elsevier
In the past few years, the growth of nanometric size drug delivery systems (DDS) has burst
into challenging innovations enabling real progresses to achieve oral delivery of anticancer …

Enhancement of transport of curcumin to brain in mice by poly(n-butylcyanoacrylate) nanoparticle

M Sun, Y Gao, C Guo, F Cao, Z Song, Y Xi, A Yu… - Journal of Nanoparticle …, 2010 - Springer
Curcumin, a widely used coloring agent and spice in food, has a potential in blocking brain
tumor formation and curing Alzheimer's disease. Due to the specific properties of blood …

PLGA 50:50 nanoparticles of paclitaxel: Development, in vitro anti-tumor activity in BT-549 cells and in vivo evaluation

RK Averineni, GV Shavi, AK Gurram… - Bulletin of Materials …, 2012 - Springer
Clinical administration of paclitaxel is hindered due to its poor solubility, which necessitates
the formulation of novel drug delivery systems to deliver such extreme hydrophobic drug. To …

Nanocapsules with specific targeting and release properties using miniemulsion polymerization

K Landfester, V Mailänder - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: The field of application for nanosized materials ranges from mere technical
purposes to a growing field of applications in biomedicine. Among the different techniques …

Nanocarriers with Multiple Cargo Load—A Comprehensive Preparation Guideline Using Orthogonal Strategies

N Hueppe, FR Wurm… - Macromolecular rapid …, 2023 - Wiley Online Library
Multifunctional nanocarriers enhance the treatment efficacy for modern therapeutics and
have gained increasing importance in biomedical research. Codelivery of multiple bioactive …

[HTML][HTML] Effect of polymeric stabilizers on the size and stability of PLGA paclitaxel nanoparticles

M Sakhi, A Khan, I Khan, SA Khan, SI Khan… - Saudi Pharmaceutical …, 2023 - Elsevier
The aim of this study is to formulate polymeric paclitaxel nanoparticles with various
stabilizers to improve solubility, enhance stability, maximize therapeutic efficacy and …

Design of self-polymerized insulin loaded poly (n-butylcyanoacrylate) nanoparticles for tunable oral delivery

H Cheng, X Zhang, L Qin, Y Huo, Z Cui, C Liu… - Journal of controlled …, 2020 - Elsevier
Macromolecular drugs, characterized by low stability and large molecular weight, still faced
various difficulties by oral administration. And controlling drugs' release rate to reach the …

Preparation of core‐shell biodegradable microfibers for long‐term drug delivery

HH Huang, CL He, HS Wang… - Journal of Biomedical …, 2009 - Wiley Online Library
A coaxial electrospun technique to fabricate core‐shell microfibers (MFs) for drug delivery
application is described. In one‐step, Paclitaxel (PTX)‐loaded poly (l‐lactic acid‐co‐ε …

[HTML][HTML] Design, preparation, and evaluation of osthol poly-butyl-cyanoacrylate nanoparticles with improved in vitro anticancer activity in neuroblastoma treatment

L Zheng, L Shen, Z Li, X Zhang, M Wu, Y Zhang, J Liu - Molecules, 2022 - mdpi.com
Osthol (osthole), known as a neuroprotective drug, has shown potent anticancer activity.
However, the potential clinical application of osthol is limited due to its low water solubility …

Synthesis and characterization of poly (methyl methacrylate) pmma and evaluation of cytotoxicity for biomedical application

PE Feuser, PC Gaspar, E Ricci‐Júnior… - Macromolecular …, 2014 - Wiley Online Library
The objective this work was the synthesis, characterization and evaluation of cytotoxicity
poly (methyl methacrylate), PMMA, nanoparticles (NPs) produced using miniemulsion …