Dopamine-loaded poly (butyl cyanoacrylate) nanoparticles reverse behavioral deficits in Parkinson's animal models
F Jahansooz, BE Hosseinzade, AH Zarmi… - Therapeutic …, 2020 - Future Science
Aim: Parkinson's disease (PD) is a neurological disorder resulting from decreased
dopamine (DA) secretion in the brain, which reflects impaired motor function. Thus, a drug …
dopamine (DA) secretion in the brain, which reflects impaired motor function. Thus, a drug …
Polybutylcyanoacrylate nanocarriers as promising targeted drug delivery systems
S Gao, Y Xu, S Asghar, M Chen, L Zou… - Journal of Drug …, 2015 - Taylor & Francis
Among the materials for preparing the polymeric nanocarriers, poly (n-butylcyanoacrylate)(
PBCA), a polymer with medium length alkyl side chain, is of lower toxicity and proper …
PBCA), a polymer with medium length alkyl side chain, is of lower toxicity and proper …
The First Step into the Brain: Uptake of NIO‐PBCA Nanoparticles by Endothelial Cells in vitro and in vivo, and Direct Evidence for their Blood–Brain Barrier Permeation
CK Weiss, MV Kohnle, K Landfester… - ChemMedChem …, 2008 - Wiley Online Library
By using fluorescent polysorbate 80 coated poly (n‐butylcyanoacrylate)(PBCA)
nanoparticles in an in vivo study, direct evidence was found for the presence of …
nanoparticles in an in vivo study, direct evidence was found for the presence of …
Combination chemotherapy of doxorubicin, all-trans retinoic acid and low molecular weight heparin based on self-assembled multi-functional polymeric nanoparticles
T Zhang, H Xiong, FZ Dahmani, L Sun, Y Li… - …, 2015 - iopscience.iop.org
Based on the complementary effects of doxorubicin (DOX), all-trans retinoic acid (ATRA) and
low molecular weight heparin (LMWH), the combination therapy of DOX, ATRA and LMWH …
low molecular weight heparin (LMWH), the combination therapy of DOX, ATRA and LMWH …
Herceptin-functionalized pure paclitaxel nanocrystals for enhanced delivery to HER2-postive breast cancer cells
The objective of this study was to prepare Herceptin (HCT)-functionalized paclitaxel
nanocrystals and evaluated their cell-specific interactions, cellular accumulation, and growth …
nanocrystals and evaluated their cell-specific interactions, cellular accumulation, and growth …
Lipid-core nanocapsules containing simvastatin improve the cognitive impairment induced by obesity and hypercholesterolemia in adult rats
R Lorenzoni, S Davies, LM Cordenonsi… - European Journal of …, 2020 - Elsevier
The development of cognitive impairment may be related to high levels of plasma
cholesterol and obesity. Simvastatin (SV) and lovastatin (LV) are drugs that can potentially …
cholesterol and obesity. Simvastatin (SV) and lovastatin (LV) are drugs that can potentially …
API-ammonium ionic liquid–Polymer compounds as a potential tool for delivery systems
M Halayqa, M Zawadzki, U Domańska… - Journal of Molecular …, 2017 - Elsevier
The objective of the present study was to synthesized a novel drug delivery system based on
ammonium ionic liquid containing active pharmaceutical ingredients (API) grafted–Poly (L …
ammonium ionic liquid containing active pharmaceutical ingredients (API) grafted–Poly (L …
Efficacy of Cisplatin-loaded poly butyl cyanoacrylate nanoparticles on the ovarian cancer: an in vitro study
SK Bagherpour Doun, SE Alavi… - Tumor Biology, 2014 - Springer
One of the main challenges of treatment of ovarian cancer is initial response to treatment
and then acquisition of resistance to Cisplatin. Nanotechnology-based approaches are …
and then acquisition of resistance to Cisplatin. Nanotechnology-based approaches are …
Paclitaxel-loaded hollow-poly (4-vinylpyridine) nanoparticles enhance drug chemotherapeutic efficacy in lung and breast cancer cell lines
R Contreras-Cáceres, MC Leiva, R Ortiz, A Díaz… - Nano Research, 2017 - Springer
Paclitaxel (PTX), one of the most effective cytotoxins for the treatment of breast and lung
cancer, is limited by its severe side effects and low tumor selectivity. In this work, hollow-poly …
cancer, is limited by its severe side effects and low tumor selectivity. In this work, hollow-poly …
Preparation, characterization and biocompatibility of poly (ethylene glycol)-poly (n-butyl cyanoacrylate) nanocapsules with oil core via miniemulsion polymerization
Y Zhang, S Zhu, L Yin, F Qian, C Tang, C Yin - European Polymer Journal, 2008 - Elsevier
A new type of nanocapsules with an oil core, coated by poly (ethylene glycol)(PEG) was
designed. The loading efficiency and the biocompatibility of the polymeric nanocapsules …
designed. The loading efficiency and the biocompatibility of the polymeric nanocapsules …