Exosomes: key players in cancer and potential therapeutic strategy

J Dai, Y Su, S Zhong, L Cong, B Liu, J Yang… - Signal transduction and …, 2020 - nature.com
Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …

Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future

SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …

The role of exosomes and their applications in cancer

Y Zhou, Y Zhang, H Gong, S Luo, Y Cui - International journal of …, 2021 - mdpi.com
Exosomes are very small extracellular vesicles secreted by multiple cell types and are
extensively distributed in various biological fluids. Recent research indicated that exosomes …

[HTML][HTML] A comprehensive review on the composition, biogenesis, purification, and multifunctional role of exosome as delivery vehicles for cancer therapy

J Li, Y Zhang, PY Dong, GM Yang… - Biomedicine & …, 2023 - Elsevier
All forms of life produce nanosized extracellular vesicles called exosomes, which are
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …

Promotion or inhibition of extracellular vesicle release: Emerging therapeutic opportunities

Y Hao, H Song, Z Zhou, X Chen, H Li, Y Zhang… - Journal of Controlled …, 2021 - Elsevier
Extracellular vesicles (EVs) are vehicles of intercellular communication that are released
from various cell types under physiological and pathological conditions, with differing effects …

Exosome-based carrier for RNA delivery: progress and challenges

Y Lu, W Huang, M Li, A Zheng - Pharmaceutics, 2023 - mdpi.com
In the last few decades, RNA-based drugs have emerged as a promising candidate to
specifically target and modulate disease-relevant genes to cure genetic defects. The key to …

Role of exosomes for delivery of chemotherapeutic drugs

A Gebeyehu, N Kommineni… - Critical Reviews™ in …, 2021 - dl.begellhouse.com
Exosomes are endogenous extracellular vesicles (30-100 nm) composed with membrane
lipid bilayer which carry vesicular proteins, enzymes, mRNA, miRNA and nucleic acids. They …

Extracellular vesicles in liquid biopsies: potential for disease diagnosis

J Liu, Y Chen, F Pei, C Zeng, Y Yao… - BioMed Research …, 2021 - Wiley Online Library
Liquid biopsy is conducted through minimally invasive or noninvasive procedures, and the
resulting material can be subjected to genomic, proteomic, and lipidomic analyses for early …

Recent progress in the theranostics application of nanomedicine in lung cancer

A Mukherjee, M Paul, S Mukherjee - Cancers, 2019 - mdpi.com
Lung cancer is one of the leading causes of cancer-related death worldwide. Non-small cell
lung cancer (NSCLC) causes around 80% to 90% of deaths. The lack of an early diagnosis …

Plant-derived exosomes: a green approach for cancer drug delivery

S Madhan, R Dhar, A Devi - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
Plant-derived exosomes (PDEs) are natural extracellular vesicles (EVs). In the current
decade, they have been highlighted for cancer therapeutic development. Cancer is a global …