The role of thyroid hormones for brain development and cognitive function

JF Rovet - Paediatric Thyroidology, 2014 - karger.com
Through its actions on regulatory genes that form, grow and sculpt the brain, thyroid
hormone (TH) is essential for human brain development. Although much of what we know …

Prevention of intellectual disability through screening for congenital hypothyroidism: how much and at what level?

SD Grosse, G Van Vliet - Archives of disease in childhood, 2011 - adc.bmj.com
Objective Congenital hypothyroidism (CHT) is a common cause of preventable mental
retardation, and the quantification of intellectual disability due to CHT is needed to assess …

Poor school performance

S Karande, M Kulkarni - The Indian Journal of Pediatrics, 2005 - Springer
Education is one of the most important aspects of human resource development. Poor
school performance not only results in the child having a low self-esteem, but also causes …

Effects of amiodarone administration during pregnancy on neonatal thyroid function and subsequent neurodevelopment

L Bartalena, F Bogazzi, LE Braverman… - Journal of …, 2001 - Springer
Amiodarone, a benzofuranic derivative, iodine-rich drug, has been used in pregnancy for
either maternal or fetal tachyarrhythmias. Amiodarone, its main metabolite …

Congenital Hypothyroidism: Influence of Disease Severity and l-Thyroxine Treatment on Intellectual, Motor, and School-Associated Outcomes in Young Adults

B Oerbeck, K Sundet, BF Kase, S Heyerdahl - Pediatrics, 2003 - publications.aap.org
Objective. To describe intellectual, motor, and school-associated outcome in young adults
with early treated congenital hypothyroidism (CH) and to study the association between long …

Influence of timing and dose of thyroid hormone replacement on mental, psychomotor, and behavioral development in children with congenital hypothyroidism

JJ Bongers-Schokking… - The Journal of …, 2005 - Elsevier
OBJECTIVES: To evaluate the influence of initial and postinitial treatment factors on
cognitive, psychomotor, and psychological outcome in schoolchildren with congenital …

Congenital hypothyroidism: a review of current diagnostic and treatment practices in relation to neuropsychologic outcome

J Rovet, D Daneman - Pediatric Drugs, 2003 - Springer
Because thyroid hormone is essential for normal brain development, children born with
congenital hypothyroidism who lack thyroid hormone during a circumscribed period of early …

The influence of etiology and treatment factors on intellectual outcome in congenital hypothyroidism

S Song, D Daneman, J Rovet - Journal of Developmental & …, 2001 - journals.lww.com
To determine the effects of hypothyroidism and hormonal patterns on outcome, we tested 65
7-to 12-year-old children with congenital hypothyroidism using standardized tests of …

Congenital hypothyroidism: an analysis of persisting deficits and associated factors

JF Rovet - Child Neuropsychology, 2002 - Taylor & Francis
Congenital hypothyroidism (CH) is a neonatal disorder that is caused by a prolonged loss of
thyroid hormone, which is essential for early brain development. While CH was once the …

Neuropsychological follow-up in early-treated congenital hypothyroidism: a problem-oriented approach

S Bargagna, G Canepa, C Costagli, D Dinetti… - Thyroid, 2000 - liebertpub.com
Screening programs for congenital hypothyroidism (CH) dramatically improved the
neuropsychological prognosis in affected children. However, mild impairments in cognitive …