Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully
understood. Besides the role of inflammatory mediators that interact with the …

Pain, particularly chronic pain, remains one of the most debilitating and difficult-to-treat
conditions in medicine. Chronic pain is difficult to treat, in part because it is associated with …

The hypothalamic neuropeptide oxytocin (OT) exerts prominent analgesic effects via central
and peripheral action. However, the precise analgesic pathways recruited by OT are largely …

Background There is a need for novel analgesics with favorable risk to benefit profiles.
Oxytocin has recently gained attention for its potential analgesic properties. Aim The aim of …

The experience of pain and pain behaviors is not only determined by physiological but also
psychosocial factors. In this context, the learning history of the individual and specifically …

Background Intimate social relationships improve individual health and longevity, an effect
which is supposed to be mediated through stress-sensitive endocrine and immune …

Introduction Oxytocin (OXT) is a peptide hormone produced in the hypothalamus that plays a
neuromodulatory role in emotion, stress, and anxiety. Due to its multidimensional role, OXT …

The aim of this randomized controlled trial was to evaluate the wound-healing effect and
antimicrobial properties of a novel stabilized hypochlorous acid solution on acute wounds …

Self-reported pain levels have been associated with increased stress levels during the
COVID-19 pandemic. Less is known about the long-term effects of stress on individuals' …

Love is probably the most fascinating feeling that a person ever experiences. However, little
is known about what is happening in the brains of a romantic couple—the central and most …