2016-08-31 Assigned to Alexo Therapeutics Inc. reassignment Alexo Therapeutics Inc.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

(57) ABSTRACT A pharmaceutical composition comprising an active agent that causes
reduction of the level of systemic immunosup pression in an individual for use intreating a …

US10112997B2 - Tight-binding agents and uses thereof - Google Patents US10112997B2 -
Tight-binding agents and uses thereof - Google Patents Tight-binding agents and uses thereof …

A pharmaceutical composition comprising an active agent that causes reduction of the level
of systemic immunosuppression in an individual for use in treating a disease, disorder …

A pharmaceutical composition comprising an active agent that causes reduction of the level
of systemic immunosuppression in an individual for use in treating a disease, disorder …

The present application relates to anti-PD-L1 antibodies, nucleic acid encoding the same,
therapeutic compositions thereof, and their use enhance T-cell function to upregulate cell …

The present specification discloses a pharmaceutical composition comprising an active
agent that causes reduction of the level of systemic immunosuppression in an individual for …

7,563,869 B2 7/2009 Honjo et al. 8,008,449 B2 8/2011 Korman et al. 8,552,154 B2 10/2013
Freeman et al. 8,629,098 B2 1/2014 Fahmy et al. 8,709,416 B2 4/2014 Langermann et al …

The present disclosure features signal-regulatory protein α (SIRPα) polypeptides and
constructs that are useful, eg, to target a cell (eg, a cancer cell or a cell of the immune …

A pharmaceutical composition comprising an active agent that causes reduction of the level
of systemic immunosuppression in an individual for use in treating a disease, disorder …