Criteria for treatment-resistant depression (TRD) and partially responsive depression (PRD)
as subtypes of major depressive disorder (MDD) are not unequivocally defined. In the …

Background Depression is common in primary care and is associated with marked personal,
social and economic morbidity, thus creating significant demands on service providers. The …

BackgroundThe Beck Depression Inventory, 2nd edition (BDI-II) is widely used in research
on depression. However, the minimal clinically important difference (MCID) is unknown …

Background Exercise is a potential treatment for depression. However, few studies have
evaluated the role of adjunct exercise in the treatment of severely major depressed …

Major depressive disorder (MDD) is among the most frequent and debilitating psychiatric
disorders. Efficacious psychotherapy and antidepressant medications have been …

Previous studies suggest that individual preferences for medication-or psychotherapy-based
treatments for depression may affect outcomes in clinical trials that compare these two forms …

Background Residual symptoms are detrimental to prognosis in major depressive disorder
(MDD); however, little is known about the contribution of each residual symptom in …

Background The Prospective Epidemiological Research on Functioning Outcomes Related
to Major Depressive Disorder (PERFORM) study has been initiated to better understand the …

Selective serotonin reuptake inhibitors (SSRIs) are first-line antidepressants, however, only
around 60% of patients could benefit from them. Acupuncture is supported by insufficient …

Objective Recent treatment guidelines have suggested that outcome should be measured in
routine clinical practice. In the present report from the Rhode Island Methods to Improve …