Prognosis and staging of AL amyloidosis
T Dittrich, C Kimmich, U Hegenbart… - Acta haematologica, 2020 - karger.com
The treatment options for systemic light chain amyloidosis (AL) are currently widening in an
unprecedented way, brought about by an expanding arsenal of anti-myeloma therapy as …
unprecedented way, brought about by an expanding arsenal of anti-myeloma therapy as …
[HTML][HTML] Light chain amyloidosis: epidemiology, staging, and prognostication
KR Baker - Methodist DeBakey Cardiovascular Journal, 2022 - ncbi.nlm.nih.gov
Amyloidosis is a disorder of protein misfolding and metabolism in which insoluble fibrils are
deposited in various tissues, causing organ dysfunction and eventually death. Out of the 60 …
deposited in various tissues, causing organ dysfunction and eventually death. Out of the 60 …
[HTML][HTML] Clinical and Cardiovascular Magnetic Resonance Imaging Features of Cardiac Amyloidosis
Amyloidosis is a systemic disease characterized by the accumulation of insoluble
aggregates in various organs, leading to parenchymal damage. When these amyloid fibrils …
aggregates in various organs, leading to parenchymal damage. When these amyloid fibrils …
How should physicians assess myocardial contraction? Redefining heart failure with a preserved ejection fraction
The most direct metric of the systolic performance of the heart is the quantity of blood ejected
by the left ventricle during a single systole (ie, the stroke volume). The stroke volume adapts …
by the left ventricle during a single systole (ie, the stroke volume). The stroke volume adapts …
Cardiac magnetic resonance imaging in appraising myocardial strain and biomechanics: a current overview
Subclinical alterations in myocardial structure and function occur early during the natural
disease course. In contrast, clinically overt signs and symptoms occur during late phases …
disease course. In contrast, clinically overt signs and symptoms occur during late phases …
Prognosis prediction in cardiac amyloidosis by cardiac magnetic resonance imaging: a systematic review with meta-analysis
P Boretto, NH Patel, K Patel, M Rana… - … Heart Journal Open, 2023 - academic.oup.com
Cardiac involvement is the foremost determinant of the clinical progression of amyloidosis.
The diagnostic role of cardiac magnetic resonance (CMR) imaging in cardiac amyloidosis …
The diagnostic role of cardiac magnetic resonance (CMR) imaging in cardiac amyloidosis …
Biomarkers in AL amyloidosis
Systemic AL amyloidosis is a rare complex hematological disorder caused by clonal plasma
cells which produce amyloidogenic immunoglobulins. Outcome and prognosis is the …
cells which produce amyloidogenic immunoglobulins. Outcome and prognosis is the …
Independent prognostic utility of 11C-Pittsburgh compound B PET in patients with light-chain cardiac amyloidosis
YJ Choi, Y Koh, HJ Lee, IC Hwang… - Journal of Nuclear …, 2022 - Soc Nuclear Med
11C-Pittsburgh compound B (PiB) PET/CT visualizes the amount of myocardial amyloid
deposit and can be used to prognosticate patients with amyloid light-chain (AL) cardiac …
deposit and can be used to prognosticate patients with amyloid light-chain (AL) cardiac …
Late gadolinium enhanced cardiac MR derived radiomics approach for predicting all-cause mortality in cardiac amyloidosis: a multicenter study
XY Zhou, CX Tang, YK Guo, WC Chen, JZ Guo… - European …, 2024 - Springer
Objectives To evaluate the prognostic value of radiomics features based on late gadolinium
enhancement (LGE) cardiac magnetic resonance (CMR) images in patients with cardiac …
enhancement (LGE) cardiac magnetic resonance (CMR) images in patients with cardiac …
Quantification of Myocardial Contraction Fraction with Three-Dimensional Automated, Machine-Learning-Based Left-Heart-Chamber Metrics: Diagnostic Utility in …
A Barbieri, JF Imberti, M Bartolomei, N Bonini… - Journal of Clinical …, 2023 - mdpi.com
Aims: The differentiation of left ventricular (LV) hypertrophic phenotypes is challenging in
patients with normal ejection fraction (EF). The myocardial contraction fraction (MCF) is a …
patients with normal ejection fraction (EF). The myocardial contraction fraction (MCF) is a …