Intranasal drug delivery: how, why and what for?

A Pires, A Fortuna, G Alves… - Journal of Pharmacy and …, 2009 - estudogeral.uc.pt
Over the recent decades the interest in intranasal delivery as a non-invasive route for drugs
is increased. Since the nasal mucosa offers numerous benefits as a target tissue for drug …

Permeability issues in nasal drug delivery

P Arora, S Sharma, S Garg - Drug discovery today, 2002 - Elsevier
The nasal route is one of the most permeable and highly vascularized site for drug
administration ensuring rapid absorption and onset of therapeutic action. It has been …

A comprehensive review of the adverse effects of systemic corticosteroids

DM Poetker, DD Reh - Otolaryngologic Clinics of North America, 2010 - oto.theclinics.com
Corticosteroids are commonly prescribed by practitioners in many medical specialties for the
treatment of chronic inflammatory conditions. The use of corticosteroids in the treatment of …

[PDF][PDF] 1 local and systemic safety of intranasal corticosteroids

J Sastre, R Mosges - Journal of Investigational Allergology and Clinical …, 2012 - jiaci.org
■ Abstract The safety and efficacy of intranasal corticosteroids (INCs) are well established
for the management of allergic rhinitis, rhinosinusitis, and nasal polyps. As seen in …

Molecular and clinical pharmacology of intranasal corticosteroids: clinical and therapeutic implications

H Derendorf, EO Meltzer - Allergy, 2008 - Wiley Online Library
Intranasal corticosteroids (INSs) are effective treatments for allergic rhinitis, rhinosinusitis,
and nasal polyposis. In recent years, increased understanding of corticosteroid and …

Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma

H Derendorf, R Nave, A Drollmann… - European …, 2006 - Eur Respiratory Soc
The pharmacokinetic and pharmacodynamic effects of inhaled corticosteroids (ICS) have
shaped the efficacy and safety of these agents in the treatment of asthma. Important …

Survey of adrenal crisis associated with inhaled corticosteroids in the United Kingdom

GRG Todd, CL Acerini, R Ross-Russell… - Archives of Disease in …, 2002 - adc.bmj.com
Background: Until recently, only two cases of acute adrenal crisis associated with inhaled
corticosteroids (ICS) had been reported worldwide. We identified four additional cases and …

Fallopia japonica Root Extract Ameliorates Ovalbumin-Induced Airway Inflammation in a CARAS Mouse Model by Modulating the IL-33/TSLP/NF-κB Signaling …

J Jin, YJ Fan, TV Nguyen, ZN Yu, CH Song… - International Journal of …, 2023 - mdpi.com
Fallopia japonica (Asian knotweed) is a medicinal herb traditionally used to treat
inflammation, among other conditions. However, the effects of F. japonica root extract (FJE) …

Nasal-nanotechnology: revolution for efficient therapeutics delivery

A Kumar, AN Pandey, SK Jain - Drug delivery, 2016 - Taylor & Francis
Context: In recent years, nanotechnology-based delivery systems have gained interest to
overcome the problems of restricted absorption of therapeutic agents from the nasal cavity …

Chronobiology and chronotherapy of allergic rhinitis and bronchial asthma

MH Smolensky, B Lemmer, AE Reinberg - Advanced drug delivery reviews, 2007 - Elsevier
Study of the chronobiology of allergic rhinitis (AR) and bronchial asthma (BA) and the
chronopharmacology and chronotherapy of the medications used in their treatment began …