[HTML][HTML] The importance of antimicrobial resistance in medical mycology

NAR Gow, C Johnson, J Berman, AT Coste… - Nature …, 2022 - nature.com
Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond

Y Lee, E Puumala, N Robbins, LE Cowen - Chemical reviews, 2020 - ACS Publications
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

[HTML][HTML] Candidiasis and Mechanisms of Antifungal Resistance

S Bhattacharya, S Sae-Tia, BC Fries - Antibiotics, 2020 - mdpi.com
Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which
is caused by more than 20 types of Candida sp., with C. albicans being the most common …

[HTML][HTML] Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in …

S Ahmad, W Alfouzan - Microorganisms, 2021 - mdpi.com
Candida auris, a recently recognized, often multidrug-resistant yeast, has become a
significant fungal pathogen due to its ability to cause invasive infections and outbreaks in …

Genome-wide analysis of experimentally evolved Candida auris reveals multiple novel mechanisms of multidrug resistance

H Carolus, S Pierson, JF Muñoz, A Subotić, RB Cruz… - MBio, 2021 - Am Soc Microbiol
Candida auris is globally recognized as an opportunistic fungal pathogen of high concern,
due to its extensive multidrug resistance (MDR). Still, molecular mechanisms of MDR are …

Candida auris and multidrug resistance: Defining the new normal

SR Lockhart - Fungal Genetics and Biology, 2019 - Elsevier
Candida auris is an emerging species of yeast characterized by colonization of skin,
persistence in the healthcare environment, and antifungal resistance. C. auris was first …

[HTML][HTML] On the emergence, spread and resistance of Candida auris: host, pathogen and environmental tipping points

A Chakrabarti, P Sood - Journal of medical microbiology, 2021 - microbiologyresearch.org
Over a decade ago, a multidrug-resistant nosocomial fungus Candida auris emerged
worldwide and has since become a significant challenge for clinicians and microbiologists …

Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

JM Rybak, JF Muñoz, KS Barker, JE Parker… - MBio, 2020 - Am Soc Microbiol
Candida auris has emerged as a multidrug-resistant pathogen of great clinical concern.
Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most …

[HTML][HTML] Drug resistance and novel therapeutic approaches in invasive candidiasis

SE Murphy, T Bicanic - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
Candida species are the leading cause of invasive fungal infections worldwide and are
associated with acute mortality rates of~ 50%. Mortality rates are further augmented in the …

Resistance to antifungal drugs

R Ben-Ami, DP Kontoyiannis - Infectious Disease Clinics, 2021 - id.theclinics.com
The burden of human disease associated with fungal infections is generally
underappreciated, with estimates indicating as many as 150 million persons infected …