[HTML][HTML] The critical role and molecular mechanisms of ferroptosis in antioxidant systems: a narrative review

M Liu, XY Kong, Y Yao, XA Wang, W Yang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Methods We searched all original papers and reviews about the molecular mechanisms of
ferroptosis in antioxidant systems using PubMed to November 2021. The search terms used …

Ferroptosis and EMT: key targets for combating cancer progression and therapy resistance

Y Ren, X Mao, H Xu, Q Dang, S Weng, Y Zhang… - Cellular and Molecular …, 2023 - Springer
Iron-dependent lipid peroxidation causes ferroptosis, a form of regulated cell death. Crucial
steps in the formation of ferroptosis include the accumulation of ferrous ions (Fe2+) and lipid …

Potential of therapeutic small molecules in apoptosis regulation in the treatment of neurodegenerative diseases: An updated review

HG Dailah - Molecules, 2022 - mdpi.com
Neurodegenerative disorders (NDs) include Parkinson's disease (PD), Alzheimer's disease
(AD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) and the common …

[HTML][HTML] Ferroptosis regulates key signaling pathways in gastrointestinal tumors: Underlying mechanisms and therapeutic strategies

R Rabitha, S Shivani, Y Showket… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Ferroptosis is an emerging novel form of non-apoptotic, regulated cell death that is heavily
dependent on iron and characterized by rupture in plasma membrane. Ferroptosis is distinct …

A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis

L Wang, H Huang, X Li, L Ouyang, X Wei, J Xie, D Liu… - Chinese Medicine, 2023 - Springer
Ferroptosis is a non-apoptotic form of regulated cell death characterized by iron-dependent
lipid peroxidation. It can be triggered by various mechanisms, including the glutathione …

[HTML][HTML] Ferritin light chain promotes the reprogramming of glioma immune microenvironment and facilitates glioma progression

H Li, C Yang, Y Wei, X Li, W Jiang, Y Xu, L Li, R Guo… - Theranostics, 2023 - ncbi.nlm.nih.gov
Background: Tumor-associated macrophages (TAMs), the most abundant non-tumor cell
population in the glioma microenvironment, play a crucial role in immune evasion and …

Immunotherapy Study on Non-small-Cell Lung Cancer (NSCLC) Combined with Cytotoxic T Cells and miRNA34a

R Pandey, CC Chiu, LF Wang - Molecular Pharmaceutics, 2024 - ACS Publications
Immunotherapy has emerged as a promising approach for cancer treatment, and the use of
microRNAs (miRNAs) as therapeutic agents has gained significant attention. In this study …

Unveiling the mechanism of action of nature-inspired anti-cancer compounds using a multi-omics approach

NC Soares, A Ali, V Srinivasulu, BM Sharaf… - Journal of …, 2022 - Elsevier
The 2020 global cancer registry has ranked breast cancer (BCa) as the most commonly
diagnosed type of cancer and the most common cause of cancer-related deaths in women …

[HTML][HTML] CircRHOT1 restricts gastric cancer cell ferroptosis by epigenetically regulating GPX4

H Wang, DA Breadner, K Deng, J Niu - Journal of Gastrointestinal …, 2023 - ncbi.nlm.nih.gov
Background Gastric cancer (GC) is a malignant form of cancer that severely threatens
human health. Despite developments on treatment, the prognosis of patients with advanced …

[HTML][HTML] Comprehensive analysis of the relationship between the ferroptosis and tumor-infiltrating immune cells, mutation, and immunotherapy in breast cancer

Z He, Z Zhou, F Wang, L Gai, Y Huang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Ferroptosis is a kind of programmed cell death that is characterized by iron
dependence. It differs from apoptosis, necrosis, autophagy, pyroptosis, and other types of …