[HTML][HTML] Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

P Düsing, A Zietzer, PR Goody, MR Hosen… - Journal of molecular …, 2021 - Springer
Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

Cardiovascular calcification heterogeneity in chronic kidney disease

JD Hutcheson, C Goettsch - Circulation Research, 2023 - Am Heart Assoc
Patients with chronic kidney disease (CKD) exhibit tremendously elevated risk for
cardiovascular disease, particularly ischemic heart disease, due to premature vascular and …

[HTML][HTML] Atherosclerotic cardiovascular disease risk assessment: An American Society for Preventive Cardiology clinical practice statement

ND Wong, MJ Budoff, K Ferdinand, IM Graham… - American journal of …, 2022 - Elsevier
Risk for atherosclerotic cardiovascular disease (ASCVD) shows considerable heterogeneity
both in generally healthy persons and in those with known ASCVD. The foundation of …

Interventions to attenuate vascular calcification progression in chronic kidney disease: a systematic review of clinical trials

C Xu, ER Smith, MK Tiong, I Ruderman… - Journal of the …, 2022 - journals.lww.com
Interventions To Attenuate Vascular Calcification Progressio... : Journal of the American
Society of Nephrology Interventions To Attenuate Vascular Calcification Progression in Chronic …

Inflammation: a putative link between phosphate metabolism and cardiovascular disease

J Voelkl, D Egli-Spichtig, I Alesutan… - Clinical Science, 2021 - portlandpress.com
Dietary habits in the western world lead to increasing phosphate intake. Under physiological
conditions, extraosseous precipitation of phosphate with calcium is prevented by a mineral …

[HTML][HTML] The importance of phosphate control in chronic kidney disease

K Tsuchiya, T Akihisa - Nutrients, 2021 - mdpi.com
A series of problems including osteopathy, abnormal serum data, and vascular calcification
associated with chronic kidney disease (CKD) are now collectively called CKD-mineral bone …

Role of Chronic Kidney Disease (CKD)–Mineral and Bone Disorder (MBD) in the Pathogenesis of Cardiovascular Disease in CKD

S Yamada, T Nakano - Journal of atherosclerosis and thrombosis, 2023 - jstage.jst.go.jp
Cardiovascular disease (CVD) is the leading cause of death in patients with chronic kidney
disease (CKD). Multiple factors account for the increased incidence of cardiovascular …

Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling

B Czaya, K Heitman, I Campos, C Yanucil, D Kentrup… - Elife, 2022 - elifesciences.org
Elevations in plasma phosphate concentrations (hyperphosphatemia) occur in chronic
kidney disease (CKD), in certain genetic disorders, and following the intake of a phosphate …

Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing …

A Chen, Z Lan, L Li, L Xie, X Liu, X Yang… - Cardiovascular …, 2023 - academic.oup.com
Aims Vascular calcification (VC) is prevalent in pathological processes such as diabetes,
chronic kidney disease (CKD), and atherosclerosis, but effective therapies are still lacking by …

Systematic review and meta-analyses of the effects of phosphate-lowering agents in nondialysis CKD

NM Lioufas, EM Pascoe, CM Hawley… - Journal of the …, 2022 - journals.lww.com
Background Benefits of phosphate-lowering interventions on clinical outcomes in patients
with CKD are unclear; systematic reviews have predominantly involved patients on dialysis …