Strategies for non-viral vectors targeting organs beyond the liver
In recent years, nanoparticles have evolved to a clinical modality to deliver diverse nucleic
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …
Non-invasive delivery strategies for biologics
AC Anselmo, Y Gokarn, S Mitragotri - Nature Reviews Drug Discovery, 2019 - nature.com
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …
clinical and commercial success, biologics are a rapidly growing class and have become a …
[HTML][HTML] Formulation, stabilisation and encapsulation of bacteriophage for phage therapy
Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …
importance of the human microbiota, there has been resurgent interest in the potential use of …
[HTML][HTML] Dry powder for pulmonary delivery: A comprehensive review
B Chaurasiya, YY Zhao - Pharmaceutics, 2021 - mdpi.com
The pulmonary route has long been used for drug administration for both local and systemic
treatment. It possesses several advantages, which can be categorized into physiological, ie …
treatment. It possesses several advantages, which can be categorized into physiological, ie …
Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases
S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
An overview of clinical and commercial impact of drug delivery systems
AC Anselmo, S Mitragotri - Journal of Controlled Release, 2014 - Elsevier
Drug delivery systems are widely researched and developed to improve the delivery of
pharmaceutical compounds and molecules. The last few decades have seen a marked …
pharmaceutical compounds and molecules. The last few decades have seen a marked …
Nano-delivery to the lung-by inhalation or other routes and why nano when micro is largely sufficient?
V Forest, J Pourchez - Advanced Drug Delivery Reviews, 2022 - Elsevier
Respiratory diseases gather a wide range of disorders which are generally difficult to treat,
partly due to a poor delivery of drugs to the lung with adequate dose and minimum side …
partly due to a poor delivery of drugs to the lung with adequate dose and minimum side …
[HTML][HTML] Recent developments in lactose blend formulations for carrier-based dry powder inhalation
GA Hebbink, M Jaspers, HJW Peters… - Advanced Drug Delivery …, 2022 - Elsevier
Lactose is the most commonly used excipient in carrier-based dry powder inhalation (DPI)
formulations. Numerous inhalation therapies have been developed using lactose as a …
formulations. Numerous inhalation therapies have been developed using lactose as a …
Formulation strategy and use of excipients in pulmonary drug delivery
G Pilcer, K Amighi - International journal of pharmaceutics, 2010 - Elsevier
Pulmonary administration of drugs presents several advantages in the treatment of many
diseases. Considering local and systemic delivery, drug inhalation enables a rapid and …
diseases. Considering local and systemic delivery, drug inhalation enables a rapid and …
[HTML][HTML] Nanotechnology-assisted metered-dose inhalers (MDIs) for high-performance pulmonary drug delivery applications
Purpose Respiratory disorders pose a major threat to the morbidity and mortality to public
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …
health. Here we reviewed the nanotechnology based pulmonary drug delivery using …