Objective: To develop a clinical practice guideline for red blood cell transfusion in adult
trauma and critical care. Design: Meetings, teleconferences and electronic-based …

Trauma patients with haemorrhagic shock who only transiently respond or do not respond to
fluid therapy and/or the administration of blood products have exsanguinating injuries …

PURPOSE: Partial nephrectomy is being increasingly performed to treat renal cell
carcinoma. Because warm ischemia is induced during many open and laparoscopic partial …

Mitochondrial dysfunction is a major contributory factor for myocardial ischemia-reperfusion
(I/R) injury. It has been reported that Pink1-Parkin-mediated mitochondrial autophagy could …

Blood transfusions are common in the hospital setting. Despite the large commitment of
resources to the delivery of blood components, many clinicians have only a vague …

Blood transfusions and blood products are often given as a life‐saving measure in patients
with critical illness. However, some patients, such as Jehovah's Witnesses, may refuse their …

Object Traumatic brain injury (TBI) often occurs as part of a multisystem trauma that may
lead to hemorrhagic shock. Effective resuscitation and restoration of oxygen delivery to the …

The goals of resuscitation in hemorrhagic shock are to correct oxygen deficit and to maintain
perfusion pressure to the vital organs. We created liposome-encapsulated hemoglobin …

Historically, exogenous administration of hemoglobin solutions to implement the oxygen
transport capacity for clinical applications suffered from dramatic drawbacks, resulting in the …

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