Role of Histone Deacetylases in the Pathogenesis of Salivary Gland Tumors and Therapeutic Targeting Options

M Manou, DS Kanakoglou, T Loupis… - International Journal of …, 2023 - mdpi.com
Salivary gland tumors (SGTs) comprise a rare and heterogenous category of
benign/malignant neoplasms with progressively increasing knowledge of the molecular …

The epigenesis of salivary glands carcinoma: from field cancerization to carcinogenesis

N Mat Lazim, A Yousaf, MAH Abusalah, S Sulong… - Cancers, 2023 - mdpi.com
Simple Summary Salivary glands carcinoma are prevalent in head and neck surgical
oncology practice. The treatment is challenging due to late diagnosis and high recurrence …

Prognostic significance of histopathological parameters for salivary gland adenoid cystic carcinoma

EF de Morais, HG de Farias Morais… - Dentistry Journal, 2023 - mdpi.com
Adenoid cystic carcinoma (ACC) is a rare salivary gland tumor that accounts for
approximately 1% of all head and neck cancers. Despite its initial indolent behavior, long …

Machine learning-based survival prediction nomogram for postoperative parotid mucoepidermoid carcinoma

Z Huang, Z Chen, Y Li, T Lin, S Cai, W Wu, L Wu… - Scientific Reports, 2024 - nature.com
Parotid mucoepidermoid carcinoma (P-MEC) is a significant histopathological subtype of
salivary gland cancer with inherent heterogeneity and complexity. Existing clinical models …

[HTML][HTML] Mutational signatures in salivary gland carcinomas

A Chrysovergis, V Papanikolaou… - Cancer Diagnosis & …, 2023 - ncbi.nlm.nih.gov
Salivary gland carcinomas belong to the head and neck carcinoma super category of
malignancies. They are characterized by histopathological diversity and comprise a variety …

[HTML][HTML] Impact of amplified oncogenes on salivary gland carcinomas

V Papanikolaou, A Chrysovergis… - Cancer Diagnosis & …, 2023 - ncbi.nlm.nih.gov
In normal epithelia, proto-oncogenes regulate critical intra-or intercellular functions,
including cell growth and proliferation, apoptosis, and signaling transduction from the cell …

Current Developments in Diagnosis of Salivary Gland Tumors: From Structure to Artificial Intelligence

AC Faur, R Buzaș, AE Lăzărescu, LA Ghenciu - Life, 2024 - mdpi.com
Salivary glands tumors are uncommon neoplasms with variable incidence, heterogenous
histologies and unpredictable biological behaviour. Most tumors are located in the parotid …

Effectiveness and risk of second primary malignancies after radiotherapy in major salivary gland carcinomas: A retrospective study using SEER database

Y Feng, K Qian, K Guo, Y Shi, J Zhou, Z Wang - Head & Neck, 2024 - Wiley Online Library
Objective To investigate the effectiveness of radiotherapy and its association with second
primary malignancies (SPMs) risk in major salivary gland carcinomas (MSGCs) patients …

[HTML][HTML] A retrospective study of nonneoplastic and neoplastic disorders of the salivary glands

S Vamesu, OA Ursica, AM Gurita, RI Voda, M Deacu… - Medicine, 2023 - journals.lww.com
The spectrum of major and minor salivary gland disorders varies widely. Epidemiological
data on some injury categories are rare and often not up-to-date. This study aims to analyze …

Application of the Milan system for reporting salivary gland cytopathology to core needle biopsies of the parotid gland

AK Israel, CC Griffith - Histopathology, 2024 - Wiley Online Library
Aims The Milan system for reporting salivary gland cytopathology was developed by an
international group of experts and first published in 2018 with the goal to standardise …