Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability
R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
Guidelines for the evaluation and management of status epilepticus
Status epilepticus (SE) treatment strategies vary substantially from one institution to another
due to the lack of data to support one treatment over another. To provide guidance for the …
due to the lack of data to support one treatment over another. To provide guidance for the …
Evidence-based guideline: treatment of convulsive status epilepticus in children and adults: report of the Guideline Committee of the American Epilepsy Society
T Glauser, S Shinnar, D Gloss, B Alldredge… - Epilepsy …, 2016 - journals.sagepub.com
CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
Drug management for acute tonic‐clonic convulsions including convulsive status epilepticus in children
A McTague, T Martland… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Tonic‐clonic convulsions and convulsive status epilepticus (currently defined
as a tonic‐clonic convulsion lasting at least 30 minutes) are medical emergencies and …
as a tonic‐clonic convulsion lasting at least 30 minutes) are medical emergencies and …
Midazolam versus diazepam for the treatment of status epilepticus in children and young adults: a meta‐analysis
J McMullan, C Sasson, A Pancioli… - Academic emergency …, 2010 - Wiley Online Library
Background: Rapid treatment of status epilepticus (SE) is associated with better outcomes.
Diazepam and midazolam are commonly used, but the optimal agent and administration …
Diazepam and midazolam are commonly used, but the optimal agent and administration …
Treatment of refractory status epilepticus: literature review and a proposed protocol
NS Abend, DJ Dlugos - Pediatric neurology, 2008 - Elsevier
Refractory status epilepticus describes continuing seizures despite adequate initial
pharmacologic treatment. This situation is common in children, but few data are available to …
pharmacologic treatment. This situation is common in children, but few data are available to …
Comparison of buccal midazolam with rectal diazepam in the treatment of prolonged seizures in Ugandan children: a randomized clinical trial
A Mpimbaza, G Ndeezi, S Staedke, PJ Rosenthal… - …, 2008 - publications.aap.org
OBJECTIVE. Our goal was to compare the efficacy and safety of buccal midazolam with
rectal diazepam in the treatment of prolonged seizures in Ugandan children. METHODS …
rectal diazepam in the treatment of prolonged seizures in Ugandan children. METHODS …
Nonintravenous midazolam versus intravenous or rectal diazepam for the treatment of early status epilepticus: a systematic review with meta-analysis
Background Prompt treatment of status epilepticus (SE) is associated with better outcomes.
Rectal diazepam (DZP) and nonintravenous (non-IV) midazolam (MDZ) are often used in the …
Rectal diazepam (DZP) and nonintravenous (non-IV) midazolam (MDZ) are often used in the …
Benzodiazepine use in seizure emergencies: a systematic review
SR Haut, S Seinfeld, J Pellock - Epilepsy & Behavior, 2016 - Elsevier
Purpose The aim of this review was to systematically examine safety and efficacy outcomes,
as well as patient/caregiver satisfaction, from clinical studies in pediatric and adult patients …
as well as patient/caregiver satisfaction, from clinical studies in pediatric and adult patients …
Time is brain: acute control of repetitive seizures and status epilepticus using alternative routes of administration of benzodiazepines
S Almohaish, M Sandler, GM Brophy - Journal of Clinical Medicine, 2021 - mdpi.com
Time plays a major role in seizure evaluation and treatment. Acute repetitive seizures and
status epilepticus are medical emergencies that require immediate assessment and …
status epilepticus are medical emergencies that require immediate assessment and …