In 2014, an extensive review discussing the major steps of cardiac development focusing on
growth, formation of primary and chamber myocardium and the development of the cardiac …

The function of a cell is defined by its intrinsic characteristics and its niche: the tissue
microenvironment in which it dwells. Here we combine single-cell and spatial …

Brugada syndrome (BrS) is a cardiac arrhythmia disorder associated with sudden death in
young adults. With the exception of SCN5A, encoding the cardiac sodium channel NaV1. 5 …

Preservation and development of life depend on the adequate segregation of sister
chromatids during mitosis and meiosis. This process is ensured by the cohesin multi-subunit …

Rationale: The cardiac conduction system (CCS) consists of distinct components including
the sinoatrial node, atrioventricular node, His bundle, bundle branches, and Purkinje fibers …

Bioelectrical impulses intrinsically generated within the sinoatrial node (SAN) trigger the
contraction of the heart in mammals. Though discovered over a century ago, the molecular …

Congenital heart diseases often involve maldevelopment of the evolutionarily recent right
heart chamber. To gain insight into right heart structure and function, we fine-tuned deep …

Hydrogels and liquid metals have been emerging as potential materials for use in self-
healing electronics. This paper presents a simple fabrication procedure for a custom …

Accidental injury to the cardiac conduction system (CCS), a network of specialized cells
embedded within the heart and indistinguishable from the surrounding heart muscle tissue …

The rate of contraction of the heart relies on proper development and function of the
sinoatrial node, which consists of a small heterogeneous cell population, including Tbx3+ …