Oligosaccharide synthesis and translational innovation
L Krasnova, CH Wong - Journal of the American Chemical Society, 2019 - ACS Publications
The translation of biological glycosylation in humans to the clinical applications involves
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
Hydrothermal pretreatment for the production of oligosaccharides: A review
P Yue, Y Hu, R Tian, J Bian, F Peng - Bioresource technology, 2022 - Elsevier
Oligosaccharides are low-molecular-weight carbohydrates with crucial physical, chemical,
and physiological properties, which are increasingly important in the fields of food …
and physiological properties, which are increasingly important in the fields of food …
Automated solution-phase multiplicative synthesis of complex glycans up to a 1,080-mer
W Yao, DC Xiong, Y Yang, C Geng, Z Cong, F Li… - Nature …, 2022 - nature.com
Carbohydrates play essential roles in nature, such as in cell–cell communication, cell growth
and immunoresponse. However, the synthesis of structurally well-defined carbohydrates …
and immunoresponse. However, the synthesis of structurally well-defined carbohydrates …
Automated glycan assembly: a perspective
M Guberman, PH Seeberger - Journal of the American Chemical …, 2019 - ACS Publications
The intrinsic complexity of carbohydrate structures has hampered access to pure glycans
and hence impeded progress in the glycosciences. Automated Glycan Assembly (AGA) has …
and hence impeded progress in the glycosciences. Automated Glycan Assembly (AGA) has …
Recent chemical synthesis and immunological evaluation of glycans related to bacterial lipopolysaccharides
C Qin, G Tian, J Hu, X Zou, J Yin - Current Opinion in Chemical Biology, 2024 - Elsevier
O-Antigens and core oligosaccharides from bacterial lipopolysaccharides (LPS) are often
structurally unique and immunologically active, have become attractive targets in the …
structurally unique and immunologically active, have become attractive targets in the …
Enzymatic and chemoenzymatic synthesis of human milk oligosaccharides and derivatives
J Zheng, H Xu, J Fang, X Zhang - Carbohydrate Polymers, 2022 - Elsevier
Human milk oligosaccharides (HMOs) are complex glycans that are the third largest solid
component in human milk. It has attracted great interest in recent years due to their critical …
component in human milk. It has attracted great interest in recent years due to their critical …
Leloir glycosyltransferases in applied biocatalysis: A multidisciplinary approach
L Mestrom, M Przypis, D Kowalczykiewicz… - International journal of …, 2019 - mdpi.com
Enzymes are nature's catalyst of choice for the highly selective and efficient coupling of
carbohydrates. Enzymatic sugar coupling is a competitive technology for industrial …
carbohydrates. Enzymatic sugar coupling is a competitive technology for industrial …
Advances in green bioproduction of marine and glycosaminoglycan oligosaccharides
C Deng, M Zhao, Q Zhao, L Zhao - Carbohydrate Polymers, 2023 - Elsevier
Functional oligosaccharides are a class of low-polymerization sugars with physiological
functions, showing great potential in the fields of food, medicine, and agriculture, with …
functions, showing great potential in the fields of food, medicine, and agriculture, with …
Recent progress in synthesis of carbohydrates with sugar nucleotide-dependent glycosyltransferases
Sugar nucleotide-dependent glycosyltransferases (GTs) are key enzymes that catalyze the
formation of glycosidic bonds in nature. They have been increasingly applied in the …
formation of glycosidic bonds in nature. They have been increasingly applied in the …
“Two Birds One Stone” Strategy for the Site-Specific Analysis of Core Fucosylation and O-GlcNAcylation
Y Luo, Y Wang, Y Tian, H Zhou… - Journal of the American …, 2023 - ACS Publications
Core fucosylation and O-GlcNAcylation are the two most famous protein glycosylation
modifications that regulate diverse physiological and pathological processes in living …
modifications that regulate diverse physiological and pathological processes in living …