The impact of insertion sequences on bacterial genome plasticity and adaptability

J Vandecraen, M Chandler, A Aertsen… - Critical reviews in …, 2017 - Taylor & Francis
Transposable elements (TE), small mobile genetic elements unable to exist independently
of the host genome, were initially believed to be exclusively deleterious genomic parasites …

Culture history and population heterogeneity as determinants of bacterial adaptation: the adaptomics of a single environmental transition

B Ryall, G Eydallin, T Ferenci - Microbiology and Molecular …, 2012 - Am Soc Microbiol
Diversity in adaptive responses is common within species and populations, especially when
the heterogeneity of the frequently large populations found in environments is considered …

The bacterial phosphotransferase system: new frontiers 50 years after its discovery

MH Saier Jr - Journal of molecular microbiology and biotechnology, 2015 - karger.com
Abstract In 1964, Kundig, Ghosh and Roseman reported the discovery of the
phosphoenolpyruvate: sugar phosphotransferase system (PTS), which they subsequently …

A novel mechanism of transposon-mediated gene activation

Z Zhang, MH Saier Jr - PLoS genetics, 2009 - journals.plos.org
Transposable Insertion Sequences (IS elements) have been shown to provide various
benefits to their hosts via gene activation or inactivation under stress conditions by …

IS5 inserts upstream of the master motility operon flhDC in a quasi-Lamarckian way

X Wang, TK Wood - The ISME journal, 2011 - academic.oup.com
Mutation rates may be influenced by the environment. Here, we demonstrate that insertion
sequence IS 5 in Escherichia coli inserts into the upstream region of the flhDC operon in a …

Zinc-Induced Transposition of Insertion Sequence Elements Contributes to Increased Adaptability of Cupriavidus metallidurans

J Vandecraen, P Monsieurs, M Mergeay… - Frontiers in …, 2016 - frontiersin.org
Bacteria can respond to adverse environments by increasing their genomic variability and
subsequently facilitating adaptive evolution. To demonstrate this, the contribution of Insertion …

Localization of Insertion Sequences in Plasmids for L-Cysteine Production in E. coli

K Heieck, T Brück - Genes, 2023 - mdpi.com
Insertion sequence elements (ISE) are often found to be responsible for the collapse of
production in synthetically engineered Escherichia coli. By the transposition of ISE into the …

Transposon-mediated adaptive and directed mutations and their potential evolutionary benefits

Z Zhang, MH Saier Jr - Journal of molecular microbiology and …, 2012 - karger.com
Transposons, mobile genetic elements that can hop from one chromosomal location to
another, are known to be both beneficial and deleterious to the cell that bears them. Their …

Hopping into a hot seat: Role of DNA structural features on IS5-mediated gene activation and inactivation under stress

MZ Humayun, Z Zhang, AM Butcher, A Moshayedi… - PLoS …, 2017 - journals.plos.org
Insertion sequence elements (IS elements) are proposed to play major roles in shaping the
genetic and phenotypic landscapes of prokaryotic cells. Recent evidence has raised the …

Comprehensive Characterization of fucAO Operon Activation in Escherichia coli

Z Zhang, J Huo, J Velo, H Zhou, A Flaherty… - International Journal of …, 2024 - mdpi.com
Wildtype Escherichia coli cells cannot grow on L-1, 2-propanediol, as the fucAO operon
within the fucose (fuc) regulon is thought to be silent in the absence of L-fucose. Little …