Creative biological lignin conversion routes toward lignin valorization
Lignin, the largest renewable aromatic resource, is a promising alternative feedstock for the
sustainable production of various chemicals, fuels, and materials. Despite this potential …
sustainable production of various chemicals, fuels, and materials. Despite this potential …
Tandem chemocatalysis and biological funneling to valorize lignin
In 2014, Linger et al. presented a tandem process for lignin valorization by integrating
chemical and biological catalysis. Chemical pretreatment of corn stover generated mixed …
chemical and biological catalysis. Chemical pretreatment of corn stover generated mixed …
Lignin conversion to β-ketoadipic acid by Pseudomonas putida via metabolic engineering and bioprocess development
Bioconversion of a heterogeneous mixture of lignin-related aromatic compounds (LRCs) to a
single product via microbial biocatalysts is a promising approach to valorize lignin. Here …
single product via microbial biocatalysts is a promising approach to valorize lignin. Here …
[HTML][HTML] Biobased PET from lignin using an engineered cis, cis-muconate-producing Pseudomonas putida strain with superior robustness, energy and redox …
M Kohlstedt, A Weimer, F Weiland, J Stolzenberger… - Metabolic …, 2022 - Elsevier
Polyethylene terephthalate (PET), the most common synthetic polyester today, is largely
produced from fossil resources, contributing to global warming. Consequently, sustainable …
produced from fossil resources, contributing to global warming. Consequently, sustainable …
[HTML][HTML] Systems metabolic engineering upgrades Corynebacterium glutamicum for selective high-level production of the chiral drug precursor and cell-protective …
S Pauli, M Kohlstedt, J Lamber, F Weiland, J Becker… - Metabolic …, 2023 - Elsevier
The nonproteinogenic cyclic metabolite l-pipecolic acid is a chiral precursor for the synthesis
of various commercial drugs and functions as a cell-protective extremolyte and mediator of …
of various commercial drugs and functions as a cell-protective extremolyte and mediator of …
Catalytic carbon–carbon bond cleavage in lignin via manganese–zirconium-mediated autoxidation
Efforts to produce aromatic monomers through catalytic lignin depolymerization have
historically focused on aryl–ether bond cleavage. A large fraction of aromatic monomers in …
historically focused on aryl–ether bond cleavage. A large fraction of aromatic monomers in …
[HTML][HTML] Systems metabolic engineering upgrades Corynebacterium glutamicum to high-efficiency cis, cis-muconic acid production from lignin-based aromatics
F Weiland, N Barton, M Kohlstedt, J Becker… - Metabolic …, 2023 - Elsevier
Lignin displays a highly challenging renewable. To date, massive amounts of lignin,
generated in lignocellulosic processing facilities, are for the most part merely burned due to …
generated in lignocellulosic processing facilities, are for the most part merely burned due to …
RB-TnSeq identifies genetic targets for improved tolerance of Pseudomonas putida towards compounds relevant to lignin conversion
Lignin-derived mixtures intended for bioconversion commonly contain high concentrations
of aromatic acids, aliphatic acids, and salts. The inherent toxicity of these chemicals places a …
of aromatic acids, aliphatic acids, and salts. The inherent toxicity of these chemicals places a …
High-level production of 2-pyrone-4, 6-dicarboxylic acid from vanillic acid as a lignin-related aromatic compound by metabolically engineered fermentation to realize …
Pyrone-4, 6-dicarboxylic acid (PDC) is a valuable building block molecule produced from
lignin-derived aromatic compounds by biological funneling. This study aimed to design a …
lignin-derived aromatic compounds by biological funneling. This study aimed to design a …
Successful selective production of vanillic acid from depolymerized sulfite lignin and its application to poly (ethylene vanillate) synthesis
Y Higuchi, H Ishimaru, T Yoshikawa, T Masuda… - Bioresource …, 2023 - Elsevier
Towards lignin upgrading, vanillic acid (VA), a lignin-derived guaiacyl compound, was
produced from sulfite lignin for successfully synthesizing poly (ethylene vanillate), an …
produced from sulfite lignin for successfully synthesizing poly (ethylene vanillate), an …