One primary goal of analyzing genomic data is the identification of biomarkers which may be
causative of, correlated with, or otherwise biologically relevant to disease phenotypes. In this …

Unraveling the complex biological mechanisms underlying human health and disease is a
great challenge. With genomic data, many aspects can be investigated in great detail, such …

The overall aim of this PhD is to use a multidisciplinary approach to determine the function of
Ulcerative Colitis (UC) associated SNPs, to help understand the role of SNPs in the …

Epistasis is a growing area of research in genome-wide studies, but the differences between
alternative definitions of epistasis remain a source of confusion for many researchers. One …

We introduce a version of the epistasis test in FaST-LMM for clusters of multithreaded
processors. This new software maintains the sensitivity of the original FaST-LMM while …

Genome-wide association studies (GWA studies or GWAS) investigate the relationships
between genetic variants such as single-nucleotide polymorphisms (SNPs) and individual …

Identifying how epistasis, non-linear genetic effects, contribute to phenotypic variance in
humans has been an enduring challenge. So far neither the computational resources that …

Objective: To investigate interactions, if any, among six functional SNPs of metabolic genes
viz. CYP2D6 (* 2,* 4,* 10) and GST (T1, M1, P1) in essential hypertensive Jat Sikh north …

COMPRESSION AND VERSION CONTROL OF BIOLOGICAL NETWORKS Page 1
COMPRESSION AND VERSION CONTROL OF BIOLOGICAL NETWORKS by TYLER COWMAN …

Advancements in high-throughput technologies and high-performance computing have
enabled the discovery of tens of thousands of genetic associations for complex traits and …