What makes the sinoatrial node tick? A question not for the faint of heart

L Donald, EG Lakatta - Philosophical Transactions of the …, 2023 - royalsocietypublishing.org
Even before the sinoatrial node (SAN) was discovered, cardiovascular science was
engaged in an active investigation of when and why the heart would beat. After the …

Updates on epicardial adipose tissue mechanisms on atrial fibrillation

M Couselo‐Seijas, M Rodríguez‐Mañero… - Obesity …, 2021 - Wiley Online Library
Obesity is a well‐known risk factor for atrial fibrillation (AF). Local epi‐myocardial or intra‐
myocardial adiposity caused by aging, obesity, or cardiovascular disease (CVD) is …

Sleep duration and atrial fibrillation risk in the context of predictive, preventive, and personalized medicine: the Suita Study and meta-analysis of prospective cohort …

A Arafa, Y Kokubo, K Shimamoto, R Kashima… - EPMA Journal, 2022 - Springer
Background Short and long sleep durations are common behaviors that could predict
several cardiovascular diseases. However, the association between sleep duration and …

The autonomic coumel triangle: a new way to define the fascinating relationship between atrial fibrillation and the autonomic nervous system

M Rebecchi, F Fanisio, F Rizzi, A Politano, E De Ruvo… - Life, 2023 - mdpi.com
Arrhythmogenic substrate, modulating factors, and triggering factors (the so-called Coumel's
triangle concept) play a primary role in atrial fibrillation (AF) pathophysiology. Several years …

Pathways and morphologic pattern of blood supply of epicardial ganglionated nerve plexus

D Kvitka, DH Pauza - Annals of Anatomy-Anatomischer Anzeiger, 2024 - Elsevier
Detailed cardiac neuroanatomy is critical for understanding cardiac function and its
pathology. However, there remains a significant gap in knowledge regarding the blood …

Analyses of m6A regulatory genes and subtype classification in atrial fibrillation

Y Zhao, Y Che, Q Liu, S Zhou, Y Xiao - Frontiers in cellular …, 2023 - frontiersin.org
Objective To explore the role of m6A regulatory genes in atrial fibrillation (AF), we classified
atrial fibrillation patients into subtypes by two genotyping methods associated with m6A …

Extracardiac vagal stimulation-assisted cardioneuroablation: Dynamically evaluating the impact of sequential ganglionated plexus ablation on vagal control of SAN …

W Chen, Z Liu, P Xiao, Y Xu, D Li, Q Xiong… - Journal of …, 2022 - mdpi.com
Cardioneuroablation (CNA) is proposed as a promising therapy for patients with sinoatrial
node dysfunction (SND) that is mediated by excessive vagal tone. However, a series of …

Autonomic imbalance and atrial ectopic activity—A pathophysiological and clinical view

A Scridon - Frontiers in Physiology, 2022 - frontiersin.org
The heart is one of the most richly innervated organs and the impact of the complex cardiac
autonomic network on atrial electrophysiology and arrhythmogenesis, including on atrial …

Analyzing the impact of sleep duration on atrial fibrillation risk: a comprehensive systematic review and meta-analysis

V Vats, V Kulkarni, MA Shafique, A Haseeb… - Irish Journal of Medical …, 2024 - Springer
Background Recent studies have suggested an association between sleep duration and
cardiovascular diseases; however, the link to AF is inconclusive. This study aimed to explore …

Resting heart rate as a preoperative predictor of postoperative atrial fibrillation after pulmonary thromboendarterectomy

Z Liu, Y Zhen, F Lin, X Zheng, X Liu… - Journal of Cardiac …, 2022 - Wiley Online Library
Background As a marker of the autonomic nervous system, resting heart rate is a predictor of
postoperative atrial fibrillation (POAF). However, its predictive value for POAF after …