Glutamine imaging: a new avenue for glioma management

S Ekici, JA Nye, SG Neill, JW Allen… - American Journal …, 2022 - Am Soc Neuroradiology
The glutamine pathway is emerging as an important marker of cancer prognosis and a target
for new treatments. In gliomas, the most common type of brain tumors, metabolic …

[HTML][HTML] In vivo brain MR spectroscopy in gliomas: clinical and pre-clinical chances

F Padelli, F Mazzi, A Erbetta, L Chiapparini… - Clinical and …, 2022 - Springer
Purpose Gliomas, the most common primary brain tumours, have recently been re-classified
incorporating molecular aspects with important clinical, prognostic, and predictive …

[HTML][HTML] Roles of strong scalar couplings in maximizing glutamate, glutamine and glutathione pseudo singlets at 7 tesla

L An, JW Evans, C Burton, JS Tomar… - Frontiers in …, 2022 - frontiersin.org
For the H4 protons of glutamate (Glu), glutamine (Gln), and the glutamyl moiety of
glutathione (GSH), the effect of the internal strong scalar coupling between the two …

Precision of metabolite‐selective MRS measurements of glutamate, GABA and glutathione: A review of human brain studies

K Kanagasabai, L Palaniyappan… - NMR in …, 2024 - Wiley Online Library
Single‐voxel proton magnetic resonance spectroscopy (SV 1H‐MRS) is an in vivo
noninvasive imaging technique used to detect neurotransmitters and metabolites. It enables …

[HTML][HTML] Detection of 13C labeling of glutamate and glutamine in human brain by proton magnetic resonance spectroscopy

L An, S Li, M Ferraris Araneta, CS Johnson, J Shen - Scientific Reports, 2022 - nature.com
A proton magnetic resonance spectroscopy (MRS) technique was used to measure 13C
enrichments of glutamate and glutamine in a 3.5× 1.8× 2 cm3 voxel placed in the dorsal …

In Vivo Measurement of 13 C Labeling of Glutamate and Glutamine in the Human Brain Using H MRS

L An, S Li, MF Araneta, M Victorino, C Johnson, J Shen - archive.ismrm.org
A recently developed single-step spectral editing 1 H MRS technique that induces intense
Glu and Gln H4 singlets at TE= 56 ms was used to measure fractional enrichments of …

In Vivo Measurement of Carbon-13 Labeling of Glutamate and Glutamine in Human Brain Using Proton Magnetic Resonance Spectroscopy

L An, S Li, MF Araneta, M Victorino, C Johnson, J Shen - 2020 - researchsquare.com
A single-step spectral editing 1 H magnetic resonance spectroscopy (MRS) technique was
used to measure fractional enrichments of glutamate and glutamine in the dorsal anterior …