Introduction: The incidence of healthcare-associated multidrug resistant bacterial infections,
particularly due to carbapenem resistant organisms, has been on the rise globally. Among …

Objectives There have been few clinical trials (CTs) on antibiotics that inform neonatal and
paediatric drug labelling. The rate of unlicensed and off-label prescribing in paediatrics …

The reduction of maternal and child mortality, which has halved worldwide in the past two
decades, is considered one of the greatest successes of the Millennium Development Goals …

Objective Bacterial Infections remains a leading cause of death in the Paediatric Intensive
Care Unit (PICU). In this era of rising antimicrobial resistance, new tools are needed to guide …

Introduction: The aim of this review is to evaluate the effectiveness of antimicrobial
stewardship (AMS) programmes in the pediatric population in improving clinical outcomes …

Objective To compare dosing guidance in the paediatric formularies of high-and middle-
income countries for 32 commonly prescribed antibiotics on the World Health Organization's …

Background There are very few options to treat multidrug-resistant bacterial infections in
children. A major barrier is the duration and complexity of regulatory trials of new antibiotics …

Background The absence of consensus for outcomes in pediatric antibiotic trials is a major
barrier to research harmonization and clinical translation. We sought to develop expert …

Background: The need for antimicrobial therapies effective against multidrug resistant
organisms for children remains unmet. Tigecycline shows antibacterial activity across a …

Antimicrobial resistance is of global concern, and preserving the ability of many
antimicrobials to kill disease-causing bacteria is likely to become more challenging over …