Abstract Background Hepatitis C virus (HCV) infection is the major cause of hepatocellular
carcinoma (HCC), a common primary liver malignancy, and the third leading cause of …

Today there is increasing evidence concerning the contribution of pro-/anti-inflammatory
cytokine balance and genetic factors in hepatitis C pathogenesis and interindividual …

Background In this study, we have evaluated the immunological status of hepatitis C virus
(HCV)-infected patients aiming at identifying putative biomarkers associated with distinct …

Interferon-γ (IFN-γ) has been implicated in liver damage in animal models and chronic
hepatitis C infection; however, the underlying mechanism is not clear. Here we examined …

BACKGROUND/AIMS: Liver regeneration following chronic injury is associated with
inflammation, the proliferation of liver progenitor (oval) cells and fibrosis. Previous studies …

The role of the endogenous interferon (IFN) system has been well characterized during IFN‐
based therapy for chronic hepatitis C virus (HCV) infection; less is known for direct‐acting …

T cell-mediated liver diseases are associated with elevated serum levels of CC chemokine
ligand 2 (CCL2)/monocyte chemoattractant protein-1 (MCP-1). However, the extent to which …

The aim of this study was to evaluate the hepatoprotective and anti‐inflammatory effects of
silybin‐phospholipids and vitamin E complex (SPV complex), by determining cytokine …

Abstract Background and Aim Recently, it has been suggested that single nucleotide
polymorphisms (SNPs) in some cytokine genes may influence the production of the …

Background: Two receptor chains, IL‐10RA and IL‐10RB, are known to mediate the
functions of interleukin‐10 (IL‐10), which has been shown to be involved in the progression …